Protein: MTPN
Myotrophin (Protein V-1)

Gene: MTPN
Organism: Homo sapiens
Interactions: 127
UniProt ID: P58546

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006417 - regulation of translation
GO:0008290 - F-actin capping protein complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

866944

CAPZB
F-actin-capping protein subunit beta

2

7

High-throughput

0.811

High

946461

RHG35
Rho GTPase-activating protein 35

2

8

High-throughput

0.737

High

946402

TF65
Transcription factor p65

1

12

Small-scale

0.724

High

946403

REL
Proto-oncogene c-Rel

1

12

Small-scale

0.724

High

703521

MK01
Mitogen-activated protein kinase 1

1

8

High-throughput

0.698

High

619017

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

2

High-throughput

0.691

High

854806

RECQ1
ATP-dependent DNA helicase Q1

1

7

High-throughput

0.691

High

866629

CAZA2
F-actin-capping protein subunit alpha-2

1

6

High-throughput

0.691

High

936976

CASP6
Caspase-6

1

1

High-throughput

0.691

High

946410

PLSI
Plastin-1

1

20

High-throughput

0.691

High

946419

DDX59
Probable ATP-dependent RNA helicase DDX59

1

4

High-throughput

0.691

High

946437

PALLD
Palladin

1

12

High-throughput

0.691

High

946447

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

2

High-throughput

0.691

High

946480

NEMO
NF-kappa-B essential modulator

1

17

High-throughput

0.691

High

946424

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

4

High-throughput

0.665

High

626138

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

19

Small-scale

0.647

High

375330

RASK
GTPase KRas

1

20

High-throughput

0.618

High

599184

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.618

High

625276

CSK22
Casein kinase II subunit alpha'

1

12

High-throughput

0.618

High

946399

CSK21
Casein kinase II subunit alpha

1

13

High-throughput

0.618

High

946407

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

7

High-throughput

0.618

High

946411

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.618

High

946426

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

946432

CSK23
Casein kinase II subunit alpha 3

1

9

High-throughput

0.618

High

943890

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

20

High-throughput

0.590

High

934352

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.575

High

946414

RHGBB
Inactive Rho GTPase-activating protein 11B

2

8

High-throughput

0.571

High

946455

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

18

High-throughput

0.555

High

913751

ZN131
Zinc finger protein 131

1

3

High-throughput

0.553

High

946469

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

5

High-throughput

0.553

High

946443

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

180761

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.536

High

213880

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

11

High-throughput

0.536

High

633304

MSH3
DNA mismatch repair protein Msh3

1

3

High-throughput

0.536

High

711291

SHC1
SHC-transforming protein 1

1

11

High-throughput

0.536

High

720748

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.536

High

946404

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

7

High-throughput

0.536

High

946408

MPP2
MAGUK p55 subfamily member 2

1

9

High-throughput

0.536

High

946413

DGUOK
Deoxyguanosine kinase, mitochondrial

1

1

High-throughput

0.536

High

946429

THNS1
Threonine synthase-like 1

1

1

High-throughput

0.536

High

946435

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

9

High-throughput

0.536

High

946436

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

3

High-throughput

0.536

High

946441

F120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma

1

3

High-throughput

0.536

High

946445

ZCCHL
Zinc finger CCCH-type antiviral protein 1-like

1

3

High-throughput

0.536

High

946448

SNX27
Sorting nexin-27

1

19

High-throughput

0.536

High

946451

DNJC2
DnaJ homolog subfamily C member 2

1

9

High-throughput

0.536

High

946453

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

8

High-throughput

0.536

High

946454

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

1

High-throughput

0.536

High

946460

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

2

High-throughput

0.536

High

946462

LANC2
LanC-like protein 2

1

1

High-throughput

0.536

High

946468

KLH42
Kelch-like protein 42

1

7

High-throughput

0.536

High

946472

DNPEP
Aspartyl aminopeptidase

1

2

High-throughput

0.536

High

946474

G3BP2
Ras GTPase-activating protein-binding protein 2

1

7

High-throughput

0.536

High

379971

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.517

High

361186

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

748690

CGL
Cystathionine gamma-lyase

1

0

High-throughput

0.513

High

892448

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.513

High

946417

BOLA3
BolA-like protein 3

1

0

High-throughput

0.513

High

946422

MET2B
tRNA N(3)-cytidine methyltransferase METTL2B

1

0

High-throughput

0.513

High

946434

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.513

High

946438

5NT3B
7-methylguanosine phosphate-specific 5'-nucleotidase

1

0

High-throughput

0.513

High

946439

PTER
N-acetyltaurine hydrolase

1

0

High-throughput

0.513

High

946446

SCLY
Selenocysteine lyase

1

0

High-throughput

0.513

High

946452

HDHD3
Haloacid dehalogenase-like hydrolase domain-containing protein 3

1

0

High-throughput

0.513

High

946463

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.513

High

946465

PNPO
Pyridoxine-5'-phosphate oxidase

1

0

High-throughput

0.513

High

946473

MCTS1
Malignant T-cell-amplified sequence 1

1

0

High-throughput

0.513

High

946476

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

657522

GCSP
Glycine dehydrogenase

1

3

High-throughput

0.489

High

946400

HTRA4
Serine protease HTRA4

1

1

High-throughput

0.489

High

946440

EFHD2
EF-hand domain-containing protein D2

1

4

High-throughput

0.489

High

946458

LRC40
Leucine-rich repeat-containing protein 40

1

6

High-throughput

0.489

High

65525

DDTL
D-dopachrome decarboxylase-like protein

1

1

High-throughput

0.479

High

176958

CE290
Centrosomal protein of 290 kDa

1

20

High-throughput

0.479

High

276767

TBCA
Tubulin-specific chaperone A

1

1

High-throughput

0.479

High

298897

DNJB5
DnaJ homolog subfamily B member 5

1

6

High-throughput

0.479

High

538921

EPB41
Protein 4.1

1

17

High-throughput

0.479

High

606516

CEBPB
CCAAT/enhancer-binding protein beta

1

10

High-throughput

0.479

High

674119

BRD2
Bromodomain-containing protein 2

1

12

High-throughput

0.479

High

772121

MSX2
Homeobox protein MSX-2

1

10

High-throughput

0.479

High

822554

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.479

High

828635

MDHC
Malate dehydrogenase, cytoplasmic

1

4

High-throughput

0.479

High

887881

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

912534

GDIR1
Rho GDP-dissociation inhibitor 1

1

2

High-throughput

0.479

High

946395

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.479

High

946397

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.479

High

946406

TRI14
Tripartite motif-containing protein 14

1

10

High-throughput

0.479

High

946409

DCTN1
Dynactin subunit 1

1

6

High-throughput

0.479

High

946412

EZH2
Histone-lysine N-methyltransferase EZH2

1

11

High-throughput

0.479

High

946418

CE170
Centrosomal protein of 170 kDa

1

20

High-throughput

0.479

High

946421

CP135
Centrosomal protein of 135 kDa

1

8

High-throughput

0.479

High

946423

SAS6
Spindle assembly abnormal protein 6 homolog

1

7

High-throughput

0.479

High

946425

BAKOR
Beclin 1-associated autophagy-related key regulator

1

1

High-throughput

0.479

High

946427

CNTRL
Centriolin

1

15

High-throughput

0.479

High

946428

NAA40
N-alpha-acetyltransferase 40

1

7

High-throughput

0.479

High

946431

CNTRB
Centrobin

1

11

High-throughput

0.479

High

946433

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

946442

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.479

High

946466

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

946467

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

20

Small-scale

0.479

High

946470

TRM7
tRNA

1

1

High-throughput

0.479

High

946471

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

946475

CE164
Centrosomal protein of 164 kDa

1

16

High-throughput

0.479

High

946479

TRAF6
TNF receptor-associated factor 6

1

14

High-throughput

0.479

High

402758

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

946398

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

946401

CYC
Cytochrome c

1

0

High-throughput

0.458

High

946405

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

946430

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

946478

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

946457

AKTIP
AKT-interacting protein

1

6

High-throughput

0.457

High

529450

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

563502

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.445

High

946396

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

14

High-throughput

0.445

High

218018

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.437

High

353162

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.437

High

946459

DNJC4
DnaJ homolog subfamily C member 4

1

9

High-throughput

0.437

High

886687

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

946449

MF14A
Hippocampus abundant transcript 1 protein

1

8

High-throughput

0.407

High

946415

NADK2
NAD kinase 2, mitochondrial

1

0

High-throughput

0.279

Low

946416

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

0

High-throughput

0.279

Low

946420

CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial

1

0

High-throughput

0.279

Low

946444

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.279

Low

946456

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

1

0

High-throughput

0.279

Low

946464

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.279

Low

946450

TM237
Transmembrane protein 237

1

0

High-throughput

0.249

Low

946477

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025