Protein: CASP5
Caspase-5 (CASP-5) (EC 3.4.22.58) (ICE(rel)-III) (Protease ICH-3) (Protease TY) [Cleaved into: Caspase-5 subunit p20; Caspase-5 subunit p10]

Gene: CASP5
Organism: Homo sapiens
Interactions: 8
UniProt ID: P51878

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

885687

CASP4
Caspase-4

2

18

High-throughput

0.811

High

908558

RHG44
Rho GTPase-activating protein 44

2

3

High-throughput

0.628

High

908560

NLRP1
NACHT, LRR and PYD domains-containing protein 1

1

20

Small-scale

0.618

High

908557

IL18
Interleukin-18

1

3

Small-scale

0.575

High

908559

PPHLN
Periphilin-1

1

0

Small-scale

0.480

High

194779

MEFV
Pyrin

1

6

Small-scale

0.479

High

908561

LACRT
Extracellular glycoprotein lacritin

2

0

High-throughput

0.328

High

219289

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025