Protein: ACACB
Acetyl-CoA carboxylase 2 (EC 6.4.1.2) (ACC-beta)

Gene: ACACB
Organism: Homo sapiens
Interactions: 127
UniProt ID: O00763

Gene Ontology (top 5):
GO:0003989 - acetyl-CoA carboxylase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135995

BPL1
Biotin--protein ligase

1

0

Small-scale

0.726

High

135964

ACACB
Acetyl-CoA carboxylase 2

1

15

Small-scale

0.692

High

136012

ACACA
Acetyl-CoA carboxylase 1

1

16

High-throughput

0.691

High

136052

COP1
E3 ubiquitin-protein ligase COP1

2

20

High-throughput

0.611

High

136010

RGS1
Regulator of G-protein signaling 1

2

0

High-throughput

0.585

High

135988

CCNF
Cyclin-F

2

5

High-throughput

0.584

High

131537

STK25
Serine/threonine-protein kinase 25

1

13

High-throughput

0.536

High

135966

DAPK3
Death-associated protein kinase 3

1

4

High-throughput

0.536

High

135975

NPTXR
Neuronal pentraxin receptor

1

1

High-throughput

0.536

High

135976

OXSR1
Serine/threonine-protein kinase OSR1

1

14

High-throughput

0.536

High

135981

THIK
3-ketoacyl-CoA thiolase, peroxisomal

1

2

High-throughput

0.536

High

135991

GSK3A
Glycogen synthase kinase-3 alpha

1

6

High-throughput

0.536

High

135992

GSK3B
Glycogen synthase kinase-3 beta

1

8

High-throughput

0.536

High

135994

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.536

High

136002

H4
Histone H4

1

6

High-throughput

0.536

High

136006

CDKL1
Cyclin-dependent kinase-like 1

1

6

High-throughput

0.536

High

136007

CDK17
Cyclin-dependent kinase 17

1

7

High-throughput

0.536

High

136009

PPARD
Peroxisome proliferator-activated receptor delta

1

1

High-throughput

0.536

High

136013

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

6

High-throughput

0.536

High

136017

KGP1
cGMP-dependent protein kinase 1

1

12

High-throughput

0.536

High

136019

TESK1
Dual specificity testis-specific protein kinase 1

1

5

High-throughput

0.536

High

136032

TSSK4
Testis-specific serine/threonine-protein kinase 4

1

4

High-throughput

0.536

High

136054

GRK7
Rhodopsin kinase GRK7

1

7

High-throughput

0.536

High

136058

THRSP
Thyroid hormone-inducible hepatic protein

1

4

High-throughput

0.536

High

136063

VRK1
Serine/threonine-protein kinase VRK1

1

9

High-throughput

0.536

High

136071

M1IP1
Mid1-interacting protein 1

1

4

High-throughput

0.536

High

136072

PAK6
Serine/threonine-protein kinase PAK 6

1

12

High-throughput

0.536

High

136073

ANLN
Anillin

1

3

High-throughput

0.536

High

136074

DUS22
Dual specificity protein phosphatase 22

1

3

High-throughput

0.536

High

136078

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.536

High

136080

KS6B2
Ribosomal protein S6 kinase beta-2

1

11

High-throughput

0.536

High

136088

KC1G3
Casein kinase I isoform gamma-3

1

10

High-throughput

0.536

High

135969

TACC1
Transforming acidic coiled-coil-containing protein 1

1

0

High-throughput

0.513

High

135974

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.513

High

135993

STK19
Inactive serine/threonine-protein kinase 19

1

0

High-throughput

0.513

High

135996

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.513

High

136022

INAVA
Innate immunity activator protein

1

0

High-throughput

0.513

High

136026

ZFY27
Protrudin

1

0

High-throughput

0.513

High

136028

NT5D1
5'-nucleotidase domain-containing protein 1

1

0

High-throughput

0.513

High

136066

RM46
Large ribosomal subunit protein mL46

1

0

High-throughput

0.513

High

136068

DOCK5
Dedicator of cytokinesis protein 5

1

0

High-throughput

0.513

High

136070

ELP3
Elongator complex protein 3

1

0

High-throughput

0.513

High

136082

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

136059

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

High-throughput

0.501

High

135982

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.493

High

136038

BN3D2
RNA 5'-monophosphate methyltransferase

1

0

High-throughput

0.493

High

136079

NPAP1
Nuclear pore-associated protein 1

1

1

High-throughput

0.489

High

135968

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.480

High

135967

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

135970

EED
Polycomb protein EED

1

13

High-throughput

0.479

High

135972

LTN1
E3 ubiquitin-protein ligase listerin

1

3

High-throughput

0.479

High

135977

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

135978

FOS
Protein c-Fos

1

1

High-throughput

0.479

High

135980

GCR
Glucocorticoid receptor

1

4

High-throughput

0.479

High

135983

ARF4
ADP-ribosylation factor 4

1

11

High-throughput

0.479

High

135987

TRI23
E3 ubiquitin-protein ligase TRIM23

1

16

High-throughput

0.479

High

135989

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

12

High-throughput

0.479

High

135998

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

7

Small-scale

0.479

High

135999

WDR5
WD repeat-containing protein 5

1

12

High-throughput

0.479

High

136001

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.479

High

136003

RBX1
E3 ubiquitin-protein ligase RBX1

1

6

High-throughput

0.479

High

136004

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

11

High-throughput

0.479

High

136008

PO5F1
POU domain, class 5, transcription factor 1

1

2

High-throughput

0.479

High

136011

RBBP4
Histone-binding protein RBBP4

1

13

High-throughput

0.479

High

136014

ERCC8
DNA excision repair protein ERCC-8

1

19

High-throughput

0.479

High

136015

HDAC1
Histone deacetylase 1

1

14

High-throughput

0.479

High

136016

PWP1
Periodic tryptophan protein 1 homolog

1

14

High-throughput

0.479

High

136018

RBBP5
Retinoblastoma-binding protein 5

1

13

High-throughput

0.479

High

136020

RBBP7
Histone-binding protein RBBP7

1

16

High-throughput

0.479

High

136021

SMU1
WD40 repeat-containing protein SMU1

1

12

High-throughput

0.479

High

136024

DCAF6
DDB1- and CUL4-associated factor 6

1

16

High-throughput

0.479

High

136027

DCA12
DDB1- and CUL4-associated factor 12

1

1

High-throughput

0.479

High

136029

DCA15
DDB1- and CUL4-associated factor 15

1

4

High-throughput

0.479

High

136030

A16L1
Autophagy-related protein 16-1

1

12

High-throughput

0.479

High

136033

BCOR
BCL-6 corepressor

1

4

High-throughput

0.479

High

136036

DET1
DET1 homolog

1

4

High-throughput

0.479

High

136039

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.479

High

136041

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

136045

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

7

High-throughput

0.479

High

136046

SLX4
Structure-specific endonuclease subunit SLX4

1

5

High-throughput

0.479

High

136047

WDTC1
WD and tetratricopeptide repeats protein 1

1

18

High-throughput

0.479

High

136050

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

136051

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

136057

DDB2
DNA damage-binding protein 2

1

20

High-throughput

0.479

High

136060

FBXW5
F-box/WD repeat-containing protein 5

1

2

High-throughput

0.479

High

136061

PF21A
PHD finger protein 21A

1

7

High-throughput

0.479

High

136062

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

12

High-throughput

0.479

High

136064

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

12

High-throughput

0.479

High

136065

PCGF1
Polycomb group RING finger protein 1

1

4

High-throughput

0.479

High

136075

DCA13
DDB1- and CUL4-associated factor 13

1

9

High-throughput

0.479

High

136077

WSB2
WD repeat and SOCS box-containing protein 2

1

11

High-throughput

0.479

High

136081

RCOR1
REST corepressor 1

1

4

High-throughput

0.479

High

136085

FBW1A
F-box/WD repeat-containing protein 1A

1

16

High-throughput

0.479

High

136087

SAR1B
Small COPII coat GTPase SAR1B

1

20

High-throughput

0.479

High

135965

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.458

High

136000

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

136035

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

136069

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

135979

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.445

High

136005

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

5

High-throughput

0.445

High

136083

PPM1H
Protein phosphatase 1H

1

1

Small-scale

0.445

High

135971

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

11

High-throughput

0.437

High

135986

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

135990

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.437

High

136025

DCA10
DDB1- and CUL4-associated factor 10

1

13

High-throughput

0.437

High

136034

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

8

Small-scale

0.437

High

136037

WDR53
WD repeat-containing protein 53

1

12

High-throughput

0.437

High

136040

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.437

High

136042

HOOK3
Protein Hook homolog 3

1

8

High-throughput

0.437

High

136043

WDR5B
WD repeat-containing protein 5B

1

12

High-throughput

0.437

High

136049

ARL10
ADP-ribosylation factor-like protein 10

1

18

High-throughput

0.437

High

136053

POC1B
POC1 centriolar protein homolog B

1

12

High-throughput

0.437

High

136055

DCAF4
DDB1- and CUL4-associated factor 4

1

3

High-throughput

0.437

High

136067

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.437

High

136086

ARL5A
ADP-ribosylation factor-like protein 5A

1

20

High-throughput

0.437

High

135973

NXPH3
Neurexophilin-3

1

0

High-throughput

0.279

Low

135985

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

135997

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.279

Low

136023

CTSRT
Cation channel sperm-associated targeting subunit tau

1

0

High-throughput

0.279

Low

136031

TM154
Transmembrane protein 154

1

0

High-throughput

0.279

Low

136044

IFNE
Interferon epsilon

1

0

High-throughput

0.279

Low

136048

SAMD3
Sterile alpha motif domain-containing protein 3

1

0

High-throughput

0.279

Low

136056

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

136084

HPCL4
Hippocalcin-like protein 4

1

0

High-throughput

0.279

Low

136076

DCA16
DDB1- and CUL4-associated factor 16

1

0

High-throughput

0.249

Low

135984

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024