Protein: MEFV
Pyrin (Marenostrin)

Gene: MEFV
Organism: Homo sapiens
Interactions: 29
UniProt ID: O15553

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0002221 - pattern recognition receptor signaling pathway
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

194793

ASC
Apoptosis-associated speck-like protein containing a CARD

6

9

Small-scale

0.954

High

194769

MEFV
Pyrin

3

17

Small-scale

0.853

High

194785

NLRP3
NACHT, LRR and PYD domains-containing protein 3

2

13

Small-scale

0.754

High

194778

CASP1
Caspase-1

4

6

Small-scale

0.686

High

194770

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

3

2

Small-scale

0.660

High

194788

NLRP1
NACHT, LRR and PYD domains-containing protein 1

1

14

Small-scale

0.618

High

194792

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

13

Small-scale

0.618

High

194781

TF65
Transcription factor p65

2

5

Small-scale

0.601

High

194771

ULK1
Serine/threonine-protein kinase ULK1

1

7

Small-scale

0.561

High

186232

SIVA
Apoptosis regulatory protein Siva

1

0

Small-scale

0.549

High

194773

H12
Histone H1.2

1

4

High-throughput

0.515

High

194776

IKBA
NF-kappa-B inhibitor alpha

1

10

Small-scale

0.515

High

194784

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.513

High

127222

LEG8
Galectin-8

1

13

Small-scale

0.501

High

194772

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

12

Small-scale

0.501

High

194775

LEG3
Galectin-3

1

13

Small-scale

0.501

High

194780

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

12

Small-scale

0.501

High

194786

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

12

Small-scale

0.501

High

194790

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

12

Small-scale

0.501

High

194791

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

12

Small-scale

0.501

High

194774

CEBPB
CCAAT/enhancer-binding protein beta

1

3

Small-scale

0.479

High

194779

CASP5
Caspase-5

1

6

Small-scale

0.479

High

194782

BECN1
Beclin-1

1

3

Small-scale

0.479

High

194783

A16L1
Autophagy-related protein 16-1

1

3

Small-scale

0.479

High

194787

KPCD2
Serine/threonine-protein kinase D2

1

7

High-throughput

0.479

High

194789

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

20

High-throughput

0.479

High

194794

COG5
Conserved oligomeric Golgi complex subunit 5

1

0

Small-scale

0.460

High

194777

1433T
14-3-3 protein theta

1

10

Small-scale

0.445

High


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Last updated: 11Aug2025