Protein: IL18
Interleukin-18 (IL-18) (Iboctadekin) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma)

Gene: IL18
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q14116

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0005125 - cytokine activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

712865

CASP1
Caspase-1

5

3

Small-scale

0.908

High

353835

I18BP
Interleukin-18-binding protein

7

0

Small-scale

0.906

High

885693

CASP4
Caspase-4

3

3

Small-scale

0.818

High

1106469

IL18R
Interleukin-18 receptor 1

3

0

Small-scale

0.628

High

561359

TDGF1
Protein Cripto

2

0

High-throughput

0.602

High

1120594

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

378565

IL1B
Interleukin-1 beta

1

0

Small-scale

0.586

High

874783

SPB4
Serpin B4

2

0

High-throughput

0.585

High

1120592

ADIRF
Adipogenesis regulatory factor

2

0

High-throughput

0.580

High

840055

CASP3
Caspase-3

1

3

Small-scale

0.575

High

908557

CASP5
Caspase-5

1

3

Small-scale

0.575

High

168688

CSKP
Peripheral plasma membrane protein CASK

1

0

High-throughput

0.518

High

943049

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

988355

RAC1
Ras-related C3 botulinum toxin substrate 1

1

0

High-throughput

0.513

High

1120593

FA24B
Protein FAM24B

1

0

High-throughput

0.513

High

788308

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

0

High-throughput

0.493

High

157353

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

371995

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

1120596

MYO10
Unconventional myosin-X

1

0

Small-scale

0.458

High

664043

PRTN3
Myeloblastin

1

0

Small-scale

0.426

High

1120595

ZN747
Zinc finger protein 747

2

0

High-throughput

0.328

High

1120597

WASC3
WASH complex subunit 3

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025