Protein: ITA6
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]

Gene: ITA6, ITGA6
Organism: Homo sapiens
Interactions: 128
UniProt ID: P23229

Gene Ontology (top 5):
GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0005925 - focal adhesion
GO:0007044 - cell-substrate junction assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

403786

ITB1
Integrin beta-1

6

20

Small-scale

0.937

High

556415

ITB4
Integrin beta-4

3

20

Small-scale

0.847

High

121107

LEG8
Galectin-8

3

20

High-throughput

0.667

High

488124

HLAC
HLA class I histocompatibility antigen, C alpha chain

3

1

High-throughput

0.667

High

533123

HLAE
HLA class I histocompatibility antigen, alpha chain E

3

1

High-throughput

0.667

High

613224

CD151
CD151 antigen

3

20

Small-scale

0.667

High

613248

PTC1
Protein patched homolog 1

3

5

High-throughput

0.667

High

613250

PON2
Serum paraoxonase/arylesterase 2

3

1

High-throughput

0.667

High

613259

BTNL8
Butyrophilin-like protein 8

3

11

High-throughput

0.667

High

613286

PICK1
PRKCA-binding protein

3

4

High-throughput

0.667

High

349879

RASK
GTPase KRas

3

20

High-throughput

0.640

High

236358

B4GT4
Beta-1,4-galactosyltransferase 4

3

0

High-throughput

0.638

High

613268

CANT1
Soluble calcium-activated nucleotidase 1

3

0

High-throughput

0.638

High

613299

PCDG5
Protocadherin gamma-A5

2

6

High-throughput

0.628

High

158155

GIPC1
PDZ domain-containing protein GIPC1

2

1

Small-scale

0.606

High

613229

CD81
CD81 antigen

2

20

Small-scale

0.601

High

348513

RASN
GTPase NRas

2

20

High-throughput

0.584

High

349128

RASH
GTPase HRas

2

13

High-throughput

0.584

High

506878

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

613238

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

50294

TSN11
Tetraspanin-11

2

20

High-throughput

0.574

High

613269

TMED6
Transmembrane emp24 domain-containing protein 6

2

2

High-throughput

0.574

High

602217

CD9
CD9 antigen

2

20

Small-scale

0.570

High

613218

PDIA3
Protein disulfide-isomerase A3

1

4

Small-scale

0.561

High

230204

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

1

High-throughput

0.536

High

328253

BY55
CD160 antigen

1

4

High-throughput

0.536

High

355016

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

4

High-throughput

0.536

High

449190

LEG1
Galectin-1

1

20

High-throughput

0.536

High

545070

PVR
Poliovirus receptor

1

2

High-throughput

0.536

High

613219

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

6

High-throughput

0.536

High

613243

ACHE
Acetylcholine receptor subunit epsilon

1

1

High-throughput

0.536

High

613254

HFE
Hereditary hemochromatosis protein

1

2

High-throughput

0.536

High

613256

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

1

7

High-throughput

0.536

High

613260

BTNL3
Butyrophilin-like protein 3

1

11

High-throughput

0.536

High

613262

TM11B
Transmembrane protease serine 11B

1

10

High-throughput

0.536

High

613264

PCD20
Protocadherin-20

1

8

High-throughput

0.536

High

613271

T106A
Transmembrane protein 106A

1

5

High-throughput

0.536

High

613272

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.536

High

613275

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

1

High-throughput

0.536

High

613277

TX101
Testis-expressed protein 101

1

4

High-throughput

0.536

High

613282

RTN4
Reticulon-4

1

3

High-throughput

0.536

High

613287

PCDBG
Protocadherin beta-16

1

6

High-throughput

0.536

High

613291

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.536

High

613294

BTNL2
Butyrophilin-like protein 2

1

11

High-throughput

0.536

High

613296

CLC4A
C-type lectin domain family 4 member A

1

6

High-throughput

0.536

High

613297

PCDB7
Protocadherin beta-7

1

6

High-throughput

0.536

High

613298

PCDB1
Protocadherin beta-1

1

6

High-throughput

0.536

High

613300

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.536

High

613278

IL25
Interleukin-25

1

0

High-throughput

0.513

High

394131

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

314467

APOM
Apolipoprotein M

1

1

High-throughput

0.489

High

514342

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

532896

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.489

High

613216

CALX
Calnexin

1

5

High-throughput

0.489

High

613220

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.489

High

613227

EP3B
Epididymal secretory protein E3-beta

1

4

High-throughput

0.489

High

613258

BRID5
BRICHOS domain-containing protein 5

1

4

High-throughput

0.489

High

613274

TSN18
Tetraspanin-18

1

20

High-throughput

0.489

High

613295

FBX2
F-box only protein 2

1

11

High-throughput

0.489

High

131208

BIN1
Myc box-dependent-interacting protein 1

1

2

Small-scale

0.481

High

120305

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

155274

NRP1
Neuropilin-1

1

4

Small-scale

0.479

High

156132

TSN4
Tetraspanin-4

1

20

Small-scale

0.479

High

171194

CTDSL
CTD small phosphatase-like protein

1

2

High-throughput

0.479

High

205052

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.479

High

318065

DIRA3
GTP-binding protein Di-Ras3

1

8

High-throughput

0.479

High

436159

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

437902

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

521726

CADH1
Cadherin-1

1

5

High-throughput

0.479

High

545210

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

562049

CD36
Platelet glycoprotein 4

1

1

Small-scale

0.479

High

564413

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

610224

CBL
E3 ubiquitin-protein ligase CBL

1

5

High-throughput

0.479

High

613217

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

613222

MAP1B
Microtubule-associated protein 1B

1

2

High-throughput

0.479

High

613225

RAB5C
Ras-related protein Rab-5C

1

6

High-throughput

0.479

High

613226

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

613228

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

613230

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.479

High

613231

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

613232

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

613234

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

613236

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

613239

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

613240

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.479

High

613241

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

613242

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

613247

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.479

High

613249

CKAP5
Cytoskeleton-associated protein 5

1

4

High-throughput

0.479

High

613251

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

613252

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

613253

CAH9
Carbonic anhydrase 9

1

6

High-throughput

0.479

High

613261

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

613267

PDC6I
Programmed cell death 6-interacting protein

1

7

High-throughput

0.479

High

613279

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

613280

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

613283

ANLN
Anillin

1

1

High-throughput

0.479

High

613288

TMPS4
Transmembrane protease serine 4

1

10

High-throughput

0.479

High

613292

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

613293

DDX20
Probable ATP-dependent RNA helicase DDX20

1

7

High-throughput

0.479

High

596456

PTMS
Parathymosin

1

0

High-throughput

0.458

High

613266

MCLN3
Mucolipin-3

1

0

High-throughput

0.458

High

613244

LG3BP
Galectin-3-binding protein

1

2

Small-scale

0.457

High

152252

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

4

High-throughput

0.445

High

209212

PSCA
Prostate stem cell antigen

1

4

High-throughput

0.445

High

326024

TSN15
Tetraspanin-15

1

20

High-throughput

0.445

High

354930

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

4

High-throughput

0.445

High

613235

TSN5
Tetraspanin-5

1

20

High-throughput

0.445

High

613223

MSS4
Guanine nucleotide exchange factor MSS4

1

3

Small-scale

0.439

High

163748

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.437

High

613233

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.437

High

613237

RB11A
Ras-related protein Rab-11A

1

4

High-throughput

0.437

High

613265

THOC2
THO complex subunit 2

1

1

High-throughput

0.437

High

613273

CCDC7
Coiled-coil domain-containing protein 7

1

5

High-throughput

0.437

High

613276

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.437

High

613284

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.437

High

613285

FBX6
F-box only protein 6

1

11

High-throughput

0.437

High

613289

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

613255

DB109
Putative beta-defensin 109B

1

3

High-throughput

0.407

High

613281

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.279

Low

613246

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.269

Low

613257

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

1

0

High-throughput

0.269

Low

613290

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

0

Small-scale

0.251

Low

100482

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

613221

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

613245

TRAF2
TNF receptor-associated factor 2

1

0

Small-scale

0.249

Low

613263

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

613270

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024