Protein: PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor)

Gene: PTTG, PTTG1IP
Organism: Homo sapiens
Interactions: 44
UniProt ID: P53801

Gene Ontology (top 5):
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006606 - protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

189476

STX7
Syntaxin-7

4

2

High-throughput

0.691

High

923477

CLC7A
C-type lectin domain family 7 member A

3

0

High-throughput

0.646

High

413465

P53
Cellular tumor antigen p53

2

0

Small-scale

0.619

High

923467

VAMP3
Vesicle-associated membrane protein 3

2

2

High-throughput

0.611

High

923475

VAMP8
Vesicle-associated membrane protein 8

2

2

High-throughput

0.611

High

188844

TMPS2
Transmembrane protease serine 2

2

0

High-throughput

0.580

High

220154

TNF14
Tumor necrosis factor ligand superfamily member 14

2

0

High-throughput

0.580

High

292596

RENR
Renin receptor

2

0

High-throughput

0.580

High

923471

AMGO1
Amphoterin-induced protein 1

2

0

High-throughput

0.580

High

353802

PTTG1
Securin

1

0

Small-scale

0.549

High

923469

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.549

High

630739

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.541

High

225974

STX6
Syntaxin-6

1

1

High-throughput

0.536

High

901144

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.536

High

923472

STX12
Syntaxin-12

1

2

High-throughput

0.536

High

923478

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

1

High-throughput

0.533

High

540373

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.513

High

698516

CALX
Calnexin

1

0

High-throughput

0.513

High

923460

SNAA
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.513

High

923462

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

384388

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.493

High

654821

PGH1
Prostaglandin G/H synthase 1

1

0

High-throughput

0.493

High

923470

Q86V38
Atrophin 1

1

0

High-throughput

0.493

High

923474

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

923480

STX8
Syntaxin-8

1

1

High-throughput

0.489

High

374494

RASH
GTPase HRas

1

3

High-throughput

0.479

High

375319

RASK
GTPase KRas

1

3

High-throughput

0.479

High

560340

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

907986

VAMP7
Vesicle-associated membrane protein 7

1

1

High-throughput

0.479

High

923461

RAB14
Ras-related protein Rab-14

1

2

High-throughput

0.479

High

390500

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

923466

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

923473

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

923479

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

923481

TX264
Testis-expressed protein 264

1

0

High-throughput

0.458

High

923465

STX3
Syntaxin-3

1

3

High-throughput

0.445

High

923463

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

923464

S13A2
Solute carrier family 13 member 2

1

0

High-throughput

0.426

High

286635

STX11
Syntaxin-11

1

3

High-throughput

0.407

High

50091

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.316

High

923468

SGCB
Beta-sarcoglycan

2

0

High-throughput

0.316

High

923476

T106C
Transmembrane protein 106C

2

0

High-throughput

0.316

High

608239

EGLN
Endoglin

1

0

High-throughput

0.279

Low

861081

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025