HitPredict - High confidence protein-protein interactions

Protein: APEL
Apelin (APJ endogenous ligand) [Cleaved into: Apelin-36; Apelin-31; Apelin-28; Apelin-13]

Gene: APEL, APLN
Organism: Homo sapiens
Interactions: 8
UniProt ID: Q9ULZ1

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002026 - regulation of the force of heart contraction
GO:0003085 - negative regulation of systemic arterial blood pressure
GO:0005102 - signaling receptor binding
GO:0005179 - hormone activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1380884	TRI63 E3 ubiquitin-protein ligase TRIM63	1	1	High-throughput	0.481	High
1419328	TRI55 Tripartite motif-containing protein 55	1	1	High-throughput	0.481	High
1418514	ACE2 Angiotensin-converting enzyme 2	1	0	Small-scale	0.426	High
1407133	MDFI MyoD family inhibitor	2	0	High-throughput	0.326	High
224051	GET3 ATPase GET3	1	0	Small-scale	0.261	Low
681548	PSA3 Proteasome subunit alpha type-3	1	0	High-throughput	0.251	Low
1372120	RBPMS RNA-binding protein with multiple splicing	1	0	High-throughput	0.251	Low
1448760	PLS4 Phospholipid scramblase 4	1	0	High-throughput	0.251	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025