Protein: ARBK2
G protein-coupled receptor kinase 3 (EC 2.7.11.15) (Beta-adrenergic receptor kinase 2) (Beta-ARK-2)

Gene: ARBK2, GRK3
Organism: Homo sapiens
Interactions: 16
UniProt ID: P35626

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0004672 - protein kinase activity
GO:0004703 - G protein-coupled receptor kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

669109

ARBK1
Beta-adrenergic receptor kinase 1

3

16

High-throughput

0.861

High

458303

ADRB2
Beta-2 adrenergic receptor

1

9

Small-scale

0.647

High

240915

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.618

High

411479

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

774820

CCR4
C-C chemokine receptor type 4

1

12

Small-scale

0.618

High

774822

CXCR4
C-X-C chemokine receptor type 4

1

12

Small-scale

0.618

High

774827

GIT1
ARF GTPase-activating protein GIT1

1

8

Small-scale

0.618

High

415389

HSPB1
Heat shock protein beta-1

1

7

High-throughput

0.541

High

774826

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

17

Small-scale

0.501

High

774819

SYUA
Alpha-synuclein

1

13

High-throughput

0.481

High

774821

PMS2
Mismatch repair endonuclease PMS2

1

2

High-throughput

0.479

High

774823

FOXO1
Forkhead box protein O1

1

10

High-throughput

0.479

High

774824

PTC1
Protein patched homolog 1

1

1

Small-scale

0.479

High

595329

H15
Histone H1.5

1

4

High-throughput

0.470

High

702885

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

774825

TX101
Testis-expressed protein 101

1

0

High-throughput

0.426

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025