Protein: MET16
RNA N(6)-adenosine-methyltransferase METTL16 (EC 2.1.1.348) (Methyltransferase 10 domain-containing protein) (Methyltransferase-like protein 16) (U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase) (EC 2.1.1.346)

Gene: MET16, METTL16
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q86W50

Gene Ontology (top 5):
GO:0001734 - mRNA m(6)A methyltransferase activity
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1271719

MEPCE
7SK snRNA methylphosphate capping enzyme

3

1

High-throughput

0.640

High

1292065

MET16
RNA N(6)-adenosine-methyltransferase METTL16

1

1

High-throughput

0.618

High

1292066

S39A9
Zinc transporter ZIP9

2

0

High-throughput

0.602

High

431179

LA
Lupus La protein

1

1

High-throughput

0.536

High

280932

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.513

High

1160193

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

422478

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1194199

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

253654

IMA7
Importin subunit alpha-7

1

0

High-throughput

0.458

High

260139

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

320712

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

472868

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

589072

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

637612

FLNA
Filamin-A

1

0

High-throughput

0.458

High

942724

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

951738

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

965072

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

1140503

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1254474

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

848515

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.426

High

922743

CCHL
Holocytochrome c-type synthase

3

0

High-throughput

0.347

High

388239

GLPA
Glycophorin-A

1

0

High-throughput

0.279

Low

1292067

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.279

Low

412197

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1248984

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025