Protein: LAP4B
Lysosomal-associated transmembrane protein 4B (Lysosome-associated transmembrane protein 4-beta)

Gene: LAP4B, LAPTM4B
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q86VI4

Gene Ontology (top 5):
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

163322

TR10B
Tumor necrosis factor receptor superfamily member 10B

3

2

High-throughput

0.667

High

332667

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.638

High

1010063

DLK1
Protein delta homolog 1

4

1

High-throughput

0.630

High

1290532

I20RA
Interleukin-20 receptor subunit alpha

2

1

High-throughput

0.628

High

1290535

PCDC2
Protocadherin alpha-C2

2

1

High-throughput

0.628

High

602896

INAR1
Interferon alpha/beta receptor 1

2

1

High-throughput

0.606

High

861669

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

11

Small-scale

0.584

High

870741

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.580

High

932694

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.580

High

1036214

NRG1
Pro-neuregulin-1, membrane-bound isoform

2

0

High-throughput

0.580

High

1120466

SCRB2
Lysosome membrane protein 2

2

0

High-throughput

0.580

High

1249936

ISLR2
Immunoglobulin superfamily containing leucine-rich repeat protein 2

2

0

High-throughput

0.580

High

1290519

CYAC3
Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3

2

0

High-throughput

0.580

High

1290537

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

0

High-throughput

0.576

High

1288428

SO6A1
Solute carrier organic anion transporter family member 6A1

2

1

High-throughput

0.574

High

245805

PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

1

0

Small-scale

0.537

High

127699

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

2

High-throughput

0.536

High

164933

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

2

High-throughput

0.536

High

376620

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

1092375

TSN31
Tetraspanin-31

1

1

High-throughput

0.536

High

1290525

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

2

High-throughput

0.536

High

1290526

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

1290531

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.536

High

1290534

PCDB1
Protocadherin beta-1

1

1

High-throughput

0.536

High

1201738

NADL2
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2

1

2

High-throughput

0.523

High

858195

BKRB1
B1 bradykinin receptor

1

0

High-throughput

0.518

High

363513

EGFR
Epidermal growth factor receptor

1

0

Small-scale

0.513

High

1007874

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1290515

LRC33
Transforming growth factor beta activator LRRC33

1

0

High-throughput

0.513

High

699793

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.493

High

1290521

EXOC4
Exocyst complex component 4

1

0

Small-scale

0.493

High

183945

S22A2
Solute carrier family 22 member 2

1

4

Small-scale

0.481

High

184018

S22A1
Solute carrier family 22 member 1

1

4

Small-scale

0.481

High

1127886

S29A2
Equilibrative nucleoside transporter 2

1

1

High-throughput

0.481

High

1290516

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.481

High

169631

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

Small-scale

0.479

High

390647

TFR1
Transferrin receptor protein 1

1

2

Small-scale

0.479

High

472090

MET
Hepatocyte growth factor receptor

1

1

Small-scale

0.479

High

484175

PGFRB
Platelet-derived growth factor receptor beta

1

3

Small-scale

0.479

High

63673

A5PKU2
TUSC5 protein

1

1

High-throughput

0.470

High

1290522

Q96FB2
SLC29A2 protein

1

1

High-throughput

0.470

High

467273

MDR1
ATP-dependent translocase ABCB1

1

0

Small-scale

0.458

High

641205

FGFR2
Fibroblast growth factor receptor 2

1

0

Small-scale

0.458

High

1290533

EXOC7
Exocyst complex component 7

1

0

Small-scale

0.458

High

1290536

SNX5
Sorting nexin-5

1

0

Small-scale

0.458

High

1244096

TMM88
Transmembrane protein 88

1

0

High-throughput

0.426

High

1290517

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.426

High

1290529

RETR1
Reticulophagy regulator 1

3

0

High-throughput

0.347

High

1290528

TM231
Transmembrane protein 231

2

0

High-throughput

0.318

High

665992

IBP5
Insulin-like growth factor-binding protein 5

2

0

High-throughput

0.316

High

1178715

ODFP4
Outer dense fiber protein 4

2

0

High-throughput

0.316

High

1195531

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

1290518

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

1290520

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.316

High

1290524

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.316

High

1290527

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

1219505

ANR22
Ankyrin repeat domain-containing protein 22

2

0

High-throughput

0.313

High

1022417

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1290530

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

0

High-throughput

0.279

Low

252876

EXOC3
Exocyst complex component 3

1

0

Small-scale

0.249

Low

551137

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.249

Low

1029108

E2F1
Transcription factor E2F1

1

0

Small-scale

0.249

Low

1290523

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025