HitPredict - High confidence protein-protein interactions

Protein: PLCH2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2)

Gene: PLCH2
Organism: Homo sapiens
Interactions: 11
UniProt ID: O75038

Gene Ontology (top 5):
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
269477	RASH GTPase HRas	1	19	Small-scale	0.647	High
269481	AGTR1 Type-1 angiotensin II receptor	1	1	High-throughput	0.541	High
269476	TNKS1 Poly [ADP-ribose] polymerase tankyrase-1	1	1	High-throughput	0.501	High
269478	P53 Cellular tumor antigen p53	1	4	High-throughput	0.479	High
269483	TPM4 Tropomyosin alpha-4 chain	1	2	High-throughput	0.479	High
269484	HNRPU Heterogeneous nuclear ribonucleoprotein U	1	6	High-throughput	0.470	High
269482	TISD mRNA decay activator protein ZFP36L2	1	0	High-throughput	0.458	High
269479	TPM3 Tropomyosin alpha-3 chain	1	2	High-throughput	0.437	High
269480	TPM2 Tropomyosin beta chain	1	2	High-throughput	0.437	High
269485	P66B Transcriptional repressor p66-beta	1	1	High-throughput	0.437	High
269486	FZR1 Fizzy-related protein homolog	1	1	High-throughput	0.437	High

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Last updated: 11Aug2025