Protein: DUS2
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2)

Gene: DUS2
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q9NX74

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002943 - tRNA dihydrouridine synthesis
GO:0003725 - double-stranded RNA binding
GO:0004860 - protein kinase inhibitor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

287168

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

1

Small-scale

0.740

High

624164

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

1

Small-scale

0.740

High

1276112

KANL1
KAT8 regulatory NSL complex subunit 1

2

0

High-throughput

0.602

High

431262

LA
Lupus La protein

1

3

High-throughput

0.536

High

405551

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

1160597

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

1255813

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

401588

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

650987

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.458

High

942924

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1387595

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

373308

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

1366787

NECT2
Nectin-2

1

0

High-throughput

0.282

High

1133698

NFIX
Nuclear factor 1 X-type

1

0

High-throughput

0.249

Low

430432

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025