Protein: IGSF8
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)

Gene: IGSF8
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q969P0

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007338 - single fertilization
GO:0007399 - nervous system development
GO:0007519 - skeletal muscle tissue development
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1241465

DGLB
Diacylglycerol lipase-beta

3

0

High-throughput

0.816

High

602274

CD9
CD9 antigen

7

19

Small-scale

0.745

High

1027852

MMRN1
Multimerin-1

2

5

High-throughput

0.726

High

1281784

TMX4
Thioredoxin-related transmembrane protein 4

2

10

High-throughput

0.726

High

1281786

TMX1
Thioredoxin-related transmembrane protein 1

2

10

High-throughput

0.726

High

354877

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

3

High-throughput

0.691

High

560088

CTLA4
Cytotoxic T-lymphocyte protein 4

1

1

High-throughput

0.691

High

930092

ACTH
Actin, gamma-enteric smooth muscle

1

5

High-throughput

0.691

High

1047376

CAYP1
Calcyphosin

1

2

High-throughput

0.691

High

1255747

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

10

High-throughput

0.691

High

1281807

ST14
Suppressor of tumorigenicity 14 protein

1

5

High-throughput

0.691

High

936068

HBA
Hemoglobin subunit alpha

3

2

High-throughput

0.667

High

1084132

OCLN
Occludin

3

2

High-throughput

0.667

High

1167886

DJC14
DnaJ homolog subfamily C member 14

3

5

High-throughput

0.667

High

887922

CD81
CD81 antigen

3

20

Small-scale

0.650

High

1147928

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

3

0

High-throughput

0.638

High

1109755

CC50B
Cell cycle control protein 50B

2

2

High-throughput

0.628

High

1259426

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

2

1

High-throughput

0.628

High

124922

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

3

High-throughput

0.618

High

134156

DDX3X
ATP-dependent RNA helicase DDX3X

1

7

High-throughput

0.618

High

177070

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

5

High-throughput

0.618

High

181726

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

7

High-throughput

0.618

High

521593

ACTN1
Alpha-actinin-1

1

10

High-throughput

0.618

High

571544

DDX5
Probable ATP-dependent RNA helicase DDX5

1

8

High-throughput

0.618

High

681968

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

High-throughput

0.618

High

725685

ACTN2
Alpha-actinin-2

1

10

High-throughput

0.618

High

886172

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.618

High

918584

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

934372

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.618

High

935082

H31
Histone H3.1

1

7

High-throughput

0.618

High

952524

H33
Histone H3.3

1

7

High-throughput

0.618

High

1032136

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

7

High-throughput

0.618

High

1067783

PDIA6
Protein disulfide-isomerase A6

1

8

High-throughput

0.618

High

1086262

H31T
Histone H3.1t

1

7

High-throughput

0.618

High

1129835

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

1159223

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.618

High

1174621

H32
Histone H3.2

1

7

High-throughput

0.618

High

1271616

DDX17
Probable ATP-dependent RNA helicase DDX17

1

8

High-throughput

0.618

High

1274395

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.618

High

1281776

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.618

High

1281777

H2B1M
Histone H2B type 1-M

1

20

High-throughput

0.618

High

1281778

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.618

High

1281782

ACE2
Angiotensin-converting enzyme 2

1

3

Small-scale

0.618

High

889356

KR107
Keratin-associated protein 10-7

3

8

High-throughput

0.616

High

889614

KR108
Keratin-associated protein 10-8

3

10

High-throughput

0.616

High

1012477

DYH14
Dynein axonemal heavy chain 14

3

2

High-throughput

0.609

High

548204

CD19
B-lymphocyte antigen CD19

2

0

High-throughput

0.602

High

1078250

EFNB3
Ephrin-B3

2

0

High-throughput

0.602

High

326168

TSN15
Tetraspanin-15

2

20

High-throughput

0.601

High

344541

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.589

High

839537

SPB9
Serpin B9

1

0

High-throughput

0.586

High

611307

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

0

High-throughput

0.580

High

152318

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

2

High-throughput

0.575

High

1189389

NT2NA
Notch homolog 2 N-terminal-like protein A

1

9

High-throughput

0.555

High

991639

KRA11
Keratin-associated protein 1-1

2

10

High-throughput

0.553

High

1154162

KRA57
Keratin-associated protein 5-7

2

9

High-throughput

0.553

High

1216367

KRA13
Keratin-associated protein 1-3

2

9

High-throughput

0.553

High

195510

DHX15
ATP-dependent RNA helicase DHX15

1

4

High-throughput

0.553

High

241603

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.553

High

420868

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.553

High

617967

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.553

High

707706

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.553

High

997843

RBBP4
Histone-binding protein RBBP4

1

4

High-throughput

0.553

High

1171112

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.553

High

1281772

H2B1A
Histone H2B type 1-A

1

20

High-throughput

0.553

High

161129

CLGN
Calmegin

1

3

High-throughput

0.536

High

497403

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.536

High

840783

DYN2
Dynamin-2

1

3

High-throughput

0.536

High

872077

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

2

High-throughput

0.536

High

1235904

CLD19
Claudin-19

1

1

High-throughput

0.536

High

1281789

CC50A
Cell cycle control protein 50A

1

2

High-throughput

0.536

High

1281798

CLC4A
C-type lectin domain family 4 member A

1

6

High-throughput

0.536

High

889857

KR109
Keratin-associated protein 10-9

1

8

High-throughput

0.523

High

156543

SCAM3
Secretory carrier-associated membrane protein 3

1

0

High-throughput

0.513

High

986100

KDSR
3-ketodihydrosphingosine reductase

1

0

High-throughput

0.513

High

1223986

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

1281785

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.513

High

1281794

NCDN
Neurochondrin

1

0

High-throughput

0.513

High

1281803

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.513

High

205797

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

211640

ACTN4
Alpha-actinin-4

1

10

High-throughput

0.479

High

235996

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.479

High

365004

FRIL
Ferritin light chain

1

2

High-throughput

0.479

High

365223

FRIH
Ferritin heavy chain

1

2

High-throughput

0.479

High

381263

TBB4A
Tubulin beta-4A chain

1

7

High-throughput

0.479

High

401026

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.479

High

418520

NPM
Nucleophosmin

1

2

High-throughput

0.479

High

428350

TBB5
Tubulin beta chain

1

7

High-throughput

0.479

High

453520

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

17

High-throughput

0.479

High

502924

MYH3
Myosin-3

1

2

High-throughput

0.479

High

516627

PABP1
Polyadenylate-binding protein 1

1

6

High-throughput

0.479

High

523920

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.479

High

525007

XRCC5
X-ray repair cross-complementing protein 5

1

5

High-throughput

0.479

High

537983

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.479

High

550886

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

582422

NUCL
Nucleolin

1

6

High-throughput

0.479

High

598261

FLNA
Filamin-A

1

17

High-throughput

0.479

High

603861

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

2

High-throughput

0.479

High

609989

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

16

High-throughput

0.479

High

618145

COF1
Cofilin-1

1

1

High-throughput

0.479

High

640140

MOES
Moesin

1

5

High-throughput

0.479

High

642498

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

644119

EF1G
Elongation factor 1-gamma

1

1

High-throughput

0.479

High

653096

CD82
CD82 antigen

1

20

Small-scale

0.479

High

671302

RL12
Large ribosomal subunit protein uL11

1

2

High-throughput

0.479

High

682926

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

16

High-throughput

0.479

High

708720

MCM5
DNA replication licensing factor MCM5

1

7

High-throughput

0.479

High

773483

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.479

High

806108

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

806954

RS9
Small ribosomal subunit protein uS4

1

2

High-throughput

0.479

High

826808

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.479

High

843319

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.479

High

853022

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

6

High-throughput

0.479

High

879315

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

3

High-throughput

0.479

High

882481

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

9

High-throughput

0.479

High

898421

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

898695

RL26
Large ribosomal subunit protein uL24

1

3

High-throughput

0.479

High

899806

RL27
Large ribosomal subunit protein eL27

1

1

High-throughput

0.479

High

904072

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

9

High-throughput

0.479

High

907437

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.479

High

913669

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.479

High

915036

RS4X
Small ribosomal subunit protein eS4, X isoform

1

2

High-throughput

0.479

High

916300

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

916748

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

923140

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.479

High

923453

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

931319

YBOX1
Y-box-binding protein 1

1

3

High-throughput

0.479

High

933557

TBA4A
Tubulin alpha-4A chain

1

10

High-throughput

0.479

High

951682

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

962266

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

8

High-throughput

0.479

High

973163

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

989885

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.479

High

1019587

ILF2
Interleukin enhancer-binding factor 2

1

5

High-throughput

0.479

High

1019869

ILF3
Interleukin enhancer-binding factor 3

1

8

High-throughput

0.479

High

1049615

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

10

High-throughput

0.479

High

1052918

FLNC
Filamin-C

1

20

High-throughput

0.479

High

1053946

CAPR1
Caprin-1

1

5

High-throughput

0.479

High

1072152

PCBP2
Poly(rC)-binding protein 2

1

7

High-throughput

0.479

High

1085871

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

1165823

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

1175079

TBA1A
Tubulin alpha-1A chain

1

9

High-throughput

0.479

High

1201120

THOC4
THO complex subunit 4

1

8

High-throughput

0.479

High

1269084

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

6

High-throughput

0.479

High

1281774

VPS35
Vacuolar protein sorting-associated protein 35

1

2

High-throughput

0.479

High

1281781

TBB6
Tubulin beta-6 chain

1

7

High-throughput

0.479

High

1281793

IBTK
Inhibitor of Bruton tyrosine kinase

1

6

High-throughput

0.479

High

1281799

RL26L
Ribosomal protein uL24-like

1

3

High-throughput

0.479

High

1281800

DYN3
Dynamin-3

1

3

High-throughput

0.479

High

1281802

COF2
Cofilin-2

1

1

High-throughput

0.479

High

1281805

RL36
Large ribosomal subunit protein eL36

1

1

High-throughput

0.479

High

889217

KR104
Keratin-associated protein 10-4

1

8

High-throughput

0.470

High

1281783

KRA24
Keratin-associated protein 2-4

1

9

High-throughput

0.470

High

391077

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

400619

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.458

High

574403

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

616445

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

702117

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.458

High

722474

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

736634

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

759765

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

790497

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

805752

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

888418

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

908066

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.458

High

910514

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.458

High

910726

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.458

High

910900

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

911207

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

920037

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

920519

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.458

High

920813

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

921922

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

922291

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

949527

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

960550

PURA
Transcriptional activator protein Pur-alpha

1

0

High-throughput

0.458

High

1281795

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.458

High

1281801

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.458

High

905541

TSN5
Tetraspanin-5

1

20

High-throughput

0.445

High

473329

KRA23
Keratin-associated protein 2-3

1

9

High-throughput

0.439

High

888954

KR103
Keratin-associated protein 10-3

1

10

High-throughput

0.439

High

1281779

KR412
Keratin-associated protein 4-12

1

10

High-throughput

0.439

High

78318

EIFCL
Eukaryotic translation initiation factor 3 subunit C-like protein

1

1

High-throughput

0.437

High

275922

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

5

High-throughput

0.437

High

355161

HBD
Hemoglobin subunit delta

1

2

High-throughput

0.437

High

453880

RU2A
U2 small nuclear ribonucleoprotein A'

1

7

High-throughput

0.437

High

489188

H14
Histone H1.4

1

9

High-throughput

0.437

High

539089

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.437

High

559463

H13
Histone H1.3

1

9

High-throughput

0.437

High

559879

H12
Histone H1.2

1

9

High-throughput

0.437

High

563170

YBOX3
Y-box-binding protein 3

1

3

High-throughput

0.437

High

575528

EGR1
Early growth response protein 1

1

2

Small-scale

0.437

High

623160

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.437

High

669441

EF1D
Elongation factor 1-delta

1

1

High-throughput

0.437

High

834441

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.437

High

852126

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

20

High-throughput

0.437

High

876028

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

High-throughput

0.437

High

912174

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

2

High-throughput

0.437

High

912349

SMD1
Small nuclear ribonucleoprotein Sm D1

1

3

High-throughput

0.437

High

912697

SMD3
Small nuclear ribonucleoprotein Sm D3

1

3

High-throughput

0.437

High

933301

TBA1B
Tubulin alpha-1B chain

1

9

High-throughput

0.437

High

941267

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

952067

SRSF3
Serine/arginine-rich splicing factor 3

1

17

High-throughput

0.437

High

971296

H11
Histone H1.1

1

9

High-throughput

0.437

High

984414

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.437

High

1034107

TCOF
Treacle protein

1

10

High-throughput

0.437

High

1048173

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

High-throughput

0.437

High

1063263

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

1

11

High-throughput

0.437

High

1073095

SF3B3
Splicing factor 3B subunit 3

1

3

High-throughput

0.437

High

1281775

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.437

High

1281780

SRSF8
Serine/arginine-rich splicing factor 8

1

7

High-throughput

0.437

High

1281788

FBX6
F-box only protein 6

1

9

High-throughput

0.437

High

1281791

ADPRS
ADP-ribosylhydrolase ARH3

1

1

High-throughput

0.437

High

1281792

TBA8
Tubulin alpha-8 chain

1

9

High-throughput

0.437

High

1281796

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

High-throughput

0.437

High

1281797

TBE
Tubulin epsilon chain

1

8

High-throughput

0.437

High

1281804

YBOX2
Y-box-binding protein 2

1

3

High-throughput

0.437

High

1281806

SP16H
FACT complex subunit SPT16

1

4

High-throughput

0.437

High

1281771

FAKD4
FAST kinase domain-containing protein 4

3

0

High-throughput

0.347

High

1025668

EI2BE
Translation initiation factor eIF2B subunit epsilon

2

0

High-throughput

0.318

High

1281790

TM160
Transmembrane protein 160

2

0

High-throughput

0.318

High

817534

RFX3
Transcription factor RFX3

1

0

High-throughput

0.279

Low

1281773

BSCL2
Seipin

1

0

High-throughput

0.279

Low

1281787

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.279

Low

595

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

305796

ELP1
Elongator complex protein 1

1

0

High-throughput

0.249

Low

578057

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.249

Low

739789

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.249

Low

963870

SET
Protein SET

1

0

High-throughput

0.249

Low

1120007

PDCD4
Programmed cell death protein 4

1

0

High-throughput

0.249

Low

1148714

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024