Protein: ATG7
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)

Gene: ATG7
Organism: Homo sapiens
Interactions: 148
UniProt ID: O95352

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000423 - mitophagy
GO:0005576 - extracellular region
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

311755

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

7

16

Small-scale

0.962

High

311758

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

7

16

Small-scale

0.961

High

311767

ATG3
Ubiquitin-like-conjugating enzyme ATG3

6

7

Small-scale

0.950

High

305873

GBRAP
Gamma-aminobutyric acid receptor-associated protein

4

16

Small-scale

0.914

High

311757

ATG10
Ubiquitin-like-conjugating enzyme ATG10

4

7

High-throughput

0.903

High

311683

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

3

16

Small-scale

0.886

High

311750

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

2

16

Small-scale

0.825

High

311756

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

2

16

Small-scale

0.825

High

311655

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

2

14

Small-scale

0.737

High

296684

ATG12
Ubiquitin-like protein ATG12

3

3

Small-scale

0.664

High

311692

FOXO1
Forkhead box protein O1

4

0

Small-scale

0.648

High

311740

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

1

Small-scale

0.641

High

311746

LGMN
Legumain

3

0

High-throughput

0.638

High

311700

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

4

High-throughput

0.628

High

311704

TRIP6
Thyroid receptor-interacting protein 6

2

1

High-throughput

0.628

High

311720

NAA40
N-alpha-acetyltransferase 40

2

1

High-throughput

0.628

High

311728

TXLNB
Beta-taxilin

2

1

High-throughput

0.628

High

226141

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.618

High

294228

RECQ4
ATP-dependent DNA helicase Q4

2

1

High-throughput

0.611

High

311671

RHG25
Rho GTPase-activating protein 25

3

4

High-throughput

0.609

High

311680

ALR
FAD-linked sulfhydryl oxidase ALR

2

0

High-throughput

0.602

High

311784

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.602

High

311666

IRF2
Interferon regulatory factor 2

1

3

High-throughput

0.586

High

311690

KPCD
Protein kinase C delta type

2

2

Small-scale

0.584

High

311725

MICU2
Calcium uptake protein 2, mitochondrial

2

1

High-throughput

0.574

High

311753

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

2

Small-scale

0.561

High

311669

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.554

High

161601

GAK
Cyclin-G-associated kinase

1

2

High-throughput

0.536

High

301166

RHBT3
Rho-related BTB domain-containing protein 3

1

2

High-throughput

0.536

High

301343

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

1

High-throughput

0.536

High

304898

DUS14
Dual specificity protein phosphatase 14

1

1

High-throughput

0.536

High

311667

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.536

High

311668

DPOD1
DNA polymerase delta catalytic subunit

1

2

High-throughput

0.536

High

311672

CASP2
Caspase-2

1

1

High-throughput

0.536

High

311673

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

1

High-throughput

0.536

High

311677

ERF
ETS domain-containing transcription factor ERF

1

1

High-throughput

0.536

High

311678

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

1

1

High-throughput

0.536

High

311695

TRI32
E3 ubiquitin-protein ligase TRIM32

1

3

High-throughput

0.536

High

311698

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

High-throughput

0.536

High

311701

PEX6
Peroxisomal ATPase PEX6

1

3

High-throughput

0.536

High

311706

EMAL3
Echinoderm microtubule-associated protein-like 3

1

1

High-throughput

0.536

High

311723

CEP97
Centrosomal protein of 97 kDa

1

1

High-throughput

0.536

High

311727

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.536

High

311730

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.536

High

311733

NEDD1
Protein NEDD1

1

1

High-throughput

0.536

High

311736

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

2

High-throughput

0.536

High

311742

FXL18
F-box/LRR-repeat protein 18

1

1

High-throughput

0.536

High

311745

IF140
Intraflagellar transport protein 140 homolog

1

2

High-throughput

0.536

High

311747

ACBD6
Acyl-CoA-binding domain-containing protein 6

1

3

High-throughput

0.536

High

311751

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.536

High

311763

IF122
Intraflagellar transport protein 122 homolog

1

1

High-throughput

0.536

High

311764

WDR6
tRNA

1

2

High-throughput

0.536

High

311773

RN181
E3 ubiquitin-protein ligase RNF181

1

1

High-throughput

0.536

High

311779

TTF2
Transcription termination factor 2

1

6

High-throughput

0.536

High

311660

P53
Cellular tumor antigen p53

1

3

Small-scale

0.534

High

311696

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.515

High

47916

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.513

High

128785

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.513

High

200457

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.513

High

300867

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.513

High

311658

TTHY
Transthyretin

1

0

High-throughput

0.513

High

311663

TSP1
Thrombospondin-1

1

0

High-throughput

0.513

High

311670

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

311684

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.513

High

311685

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

311686

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.513

High

311687

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.513

High

311688

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

311697

CLN3
Battenin

1

0

High-throughput

0.513

High

311702

CND1
Condensin complex subunit 1

1

0

High-throughput

0.513

High

311703

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.513

High

311705

CTC1
CST complex subunit CTC1

1

0

High-throughput

0.513

High

311713

MAP1S
Microtubule-associated protein 1S

1

0

High-throughput

0.513

High

311714

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.513

High

311716

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

0

High-throughput

0.513

High

311718

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

311719

TEDC1
Tubulin epsilon and delta complex protein 1

1

0

High-throughput

0.513

High

311721

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.513

High

311726

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

0

High-throughput

0.513

High

311729

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

311731

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.513

High

311735

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

1

0

High-throughput

0.513

High

311739

HPS3
BLOC-2 complex member HPS3

1

0

High-throughput

0.513

High

311744

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

0

High-throughput

0.513

High

311748

SPXN
Spexin

1

0

High-throughput

0.513

High

311749

TCAB1
Telomerase Cajal body protein 1

1

0

High-throughput

0.513

High

311752

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

311759

FA83D
Protein FAM83D

1

0

High-throughput

0.513

High

311761

ZN703
Zinc finger protein 703

1

0

High-throughput

0.513

High

311762

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

0

High-throughput

0.513

High

311765

M1IP1
Mid1-interacting protein 1

1

0

High-throughput

0.513

High

311768

SMC4
Structural maintenance of chromosomes protein 4

1

0

High-throughput

0.513

High

311769

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.513

High

311770

UCKL1
Uridine-cytidine kinase-like 1

1

0

High-throughput

0.513

High

311771

NALP2
NACHT, LRR and PYD domains-containing protein 2

1

0

High-throughput

0.513

High

311780

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

311781

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

311783

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.513

High

311661

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

311691

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.493

High

276350

AP1G2
AP-1 complex subunit gamma-like 2

1

1

High-throughput

0.489

High

311681

DLX6
Homeobox protein DLX-6

1

6

High-throughput

0.489

High

311693

TBL3
Transducin beta-like protein 3

1

1

High-throughput

0.489

High

311708

ANR39
Ankyrin repeat domain-containing protein 39

1

5

High-throughput

0.489

High

311734

SHKB1
SH3KBP1-binding protein 1

1

2

High-throughput

0.489

High

311766

TF7L2
Transcription factor 7-like 2

1

1

High-throughput

0.489

High

276128

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

2

Small-scale

0.479

High

311656

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

311659

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

311665

PSG1
Pregnancy-specific beta-1-glycoprotein 1

1

1

High-throughput

0.479

High

311679

CASP9
Caspase-9

1

1

Small-scale

0.479

High

311689

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

311699

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

311717

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

311774

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

311775

HERC5
E3 ISG15--protein ligase HERC5

1

11

Small-scale

0.479

High

311777

APC7
Anaphase-promoting complex subunit 7

1

3

High-throughput

0.479

High

299299

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

311657

IL1B
Interleukin-1 beta

1

0

Small-scale

0.458

High

311662

LYN
Tyrosine-protein kinase Lyn

1

0

Small-scale

0.458

High

311664

HEM4
Uroporphyrinogen-III synthase

1

0

High-throughput

0.458

High

311682

GSDMD
Gasdermin-D

1

0

Small-scale

0.458

High

311743

VP13A
Intermembrane lipid transfer protein VPS13A

1

0

Small-scale

0.458

High

311724

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.445

High

243742

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.437

High

311737

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

2

High-throughput

0.437

High

311707

Q4KMX6
ANAPC7 protein

1

3

High-throughput

0.407

High

311715

K0930
Uncharacterized protein KIAA0930

3

0

High-throughput

0.347

High

311776

RWD2A
RWD domain-containing protein 2A

3

0

High-throughput

0.345

High

311674

KCNJ5
G protein-activated inward rectifier potassium channel 4

2

0

High-throughput

0.328

High

311711

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

2

0

High-throughput

0.328

High

311732

STXB6
Syntaxin-binding protein 6

2

0

High-throughput

0.328

High

159308

PLD2
Phospholipase D2

1

0

High-throughput

0.279

Low

311675

PRI1
DNA primase small subunit

1

0

High-throughput

0.279

Low

311676

PRI2
DNA primase large subunit

1

0

High-throughput

0.279

Low

311694

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

311709

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.279

Low

311710

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

0

High-throughput

0.279

Low

311712

F91A1
Protein FAM91A1

1

0

High-throughput

0.279

Low

311722

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.279

Low

311738

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.279

Low

311741

CC120
Coiled-coil domain-containing protein 120

1

0

High-throughput

0.279

Low

311754

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

311760

ESRP2
Epithelial splicing regulatory protein 2

1

0

High-throughput

0.279

Low

311772

TRM1
tRNA

1

0

High-throughput

0.279

Low

311778

AT7L1
Ataxin-7-like protein 1

1

0

High-throughput

0.279

Low

311782

SALL2
Sal-like protein 2

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024