HitPredict
Protein: E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Serine/threonine-protein kinase TIK) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)

Gene: E2AK2, Eif2ak2
Organism: Mus musculus
Interactions: 8
UniProt ID: Q03963

Gene Ontology (top 5):
GO:0001819 - positive regulation of cytokine production
GO:0003725 - double-stranded RNA binding
GO:0004672 - protein kinase activity
GO:0004694 - eukaryotic translation initiation factor 2alpha kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

1044578

 NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

7

Small-scale

 0.665

High

312144

 IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

20

Small-scale

 0.618

High

772553

 IRS1
Insulin receptor substrate 1

1

13

Small-scale

 0.618

High

312488

 NEMO
NF-kappa-B essential modulator

1

13

Small-scale

 0.479

High

1044574

 STING
Stimulator of interferon genes protein

1

2

High-throughput

 0.479

High

1044575

 HECD3
E3 ubiquitin-protein ligase HECTD3

1

20

Small-scale

 0.479

High

1044576

 NPM
Nucleophosmin

1

7

Small-scale

 0.479

High

1044577

 FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

 0.479

High

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Last updated: 11Aug2025