Protein: IL4
Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (BSF-1) (Binetrakin) (Lymphocyte stimulatory factor 1) (Pitrakinra)

Gene: IL4
Organism: Homo sapiens
Interactions: 19
UniProt ID: P05112

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001774 - microglial cell activation
GO:0002227 - innate immune response in mucosa
GO:0002230 - positive regulation of defense response to virus by host
GO:0002674 - negative regulation of acute inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396848

IL4RA
Interleukin-4 receptor subunit alpha

10

3

Small-scale

0.973

High

396851

I13R1
Interleukin-13 receptor subunit alpha-1

1

3

Small-scale

0.618

High

344405

A2MG
Alpha-2-macroglobulin

2

0

Small-scale

0.569

High

396849

IL2RG
Cytokine receptor common subunit gamma

1

3

Small-scale

0.536

High

396843

IRF1
Interferon regulatory factor 1

1

3

Small-scale

0.515

High

396844

IRF2
Interferon regulatory factor 2

1

3

Small-scale

0.515

High

317887

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

2

Small-scale

0.479

High

396845

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.479

High

396846

EGR1
Early growth response protein 1

1

1

Small-scale

0.479

High

396847

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

1

Small-scale

0.479

High

396850

CEBPG
CCAAT/enhancer-binding protein gamma

1

1

Small-scale

0.479

High

396853

TF65
Transcription factor p65

1

2

Small-scale

0.479

High

396854

EGR3
Early growth response protein 3

1

1

Small-scale

0.479

High

396856

IRF4
Interferon regulatory factor 4

1

3

Small-scale

0.479

High

396842

MYB
Transcriptional activator Myb

1

0

Small-scale

0.458

High

396852

CREM
cAMP-responsive element modulator

1

0

Small-scale

0.458

High

396855

EP300
Histone acetyltransferase p300

1

0

Small-scale

0.458

High

396857

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

396841

CP2E1
Cytochrome P450 2E1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024