HitPredict
Protein: DTX3L
E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L)

Gene: DTX3L
Organism: Mus musculus
Interactions: 7
UniProt ID: Q3UIR3

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0002230 - positive regulation of defense response to virus by host
GO:0004842 - ubiquitin-protein transferase activity
GO:0004857 - enzyme inhibitor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

1188097

 STING
Stimulator of interferon genes protein

2

0

High-throughput

 0.547

High

312494

 NEMO
NF-kappa-B essential modulator

1

1

Small-scale

 0.479

High

431344

 SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

Small-scale

 0.479

High

660973

 IRF8
Interferon regulatory factor 8

1

1

High-throughput

 0.479

High

1190289

 TBK1
Serine/threonine-protein kinase TBK1

1

2

Small-scale

 0.479

High

1000252

 TANK
TRAF family member-associated NF-kappa-B activator

1

0

Small-scale

 0.458

High

1190290

 GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

 0.458

High

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Last updated: 11Aug2025