Protein: TIM50
Mitochondrial import inner membrane translocase subunit TIM50

Gene: TIM50
Organism: Saccharomyces cerevisiae S288C
Interactions: 96
UniProt ID: Q02776

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
GO:0006886 - intracellular protein transport
GO:0030150 - protein import into mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

972437

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

5

7

Small-scale

0.914

High

699976

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

41

3

Small-scale

0.771

High

761887

TIM17
Mitochondrial import inner membrane translocase subunit TIM17

9

1

Small-scale

0.749

High

860225

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

10

0

Small-scale

0.724

High

792676

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

5

0

Small-scale

0.681

High

478458

HSP77
Import motor subunit, mitochondrial

3

4

Small-scale

0.646

High

826174

TOM22
Mitochondrial import receptor subunit TOM22

4

0

Small-scale

0.643

High

733691

PAM17
Presequence translocated-associated motor subunit PAM17, mitochondrial

3

0

Small-scale

0.638

High

619763

TOM40
Mitochondrial import receptor subunit TOM40

3

0

Small-scale

0.628

High

333600

CYB2
L-lactate dehydrogenase

3

0

Small-scale

0.613

High

424124

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

2

1

Small-scale

0.584

High

967645

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

2

1

Small-scale

0.584

High

576005

ADT2
ADP,ATP carrier protein 2

2

4

Small-scale

0.571

High

373287

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

0

Small-scale

0.569

High

435487

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

2

0

Small-scale

0.559

High

687842

MSS51
Protein MSS51, mitochondrial

2

0

Small-scale

0.559

High

705561

HSP78
Heat shock protein 78, mitochondrial

2

0

High-throughput

0.559

High

765528

OXA1
Mitochondrial inner membrane protein OXA1

2

0

Small-scale

0.559

High

972447

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

2

0

Small-scale

0.559

High

772730

MPM1
Mitochondrial peculiar membrane protein 1

2

0

High-throughput

0.547

High

860021

JAC1
J-type co-chaperone JAC1, mitochondrial

2

0

Small-scale

0.547

High

767714

IMB4
Importin subunit beta-4

2

2

High-throughput

0.521

High

588202

HSP60
Heat shock protein 60, mitochondrial

1

0

Small-scale

0.480

High

423043

TOM70
Mitochondrial import receptor subunit TOM70

1

1

Small-scale

0.479

High

544279

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

599500

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.479

High

731075

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

599379

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.458

High

689539

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

732965

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

735236

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.458

High

735473

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

748037

MBA1
Inner membrane mitoribosome receptor MBA1, mitochondrial

1

0

High-throughput

0.458

High

765904

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

0

Small-scale

0.458

High

864357

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

972444

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

972452

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

494764

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

503128

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.445

High

619627

MPCP
Mitochondrial phosphate carrier protein

1

5

High-throughput

0.445

High

687654

OAC1
Mitochondrial oxaloacetate transport protein

1

6

High-throughput

0.445

High

743480

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

2

High-throughput

0.445

High

751412

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.445

High

972091

IRC15
Increased recombination centers protein 15

1

0

High-throughput

0.438

High

485811

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.437

High

606728

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

4

High-throughput

0.437

High

628387

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

730895

CENPA
Histone H3-like centromeric protein CSE4

1

2

High-throughput

0.437

High

762491

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

972442

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.437

High

972445

IMB1
Importin subunit beta-1

1

3

High-throughput

0.437

High

972449

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.437

High

860005

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.426

High

962621

ACAC
Acetyl-CoA carboxylase

1

0

High-throughput

0.426

High

691109

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.417

High

731350

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.417

High

743646

HMT1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.417

High

754284

MED6
Mediator of RNA polymerase II transcription subunit 6

1

1

High-throughput

0.417

High

972448

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

1

High-throughput

0.417

High

333887

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.407

High

333988

ADH2
Alcohol dehydrogenase 2

1

1

High-throughput

0.407

High

360998

TBB
Tubulin beta chain

1

3

High-throughput

0.407

High

454436

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.407

High

472546

YD14B
Transposon Ty1-DR5 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

472556

YD15B
Transposon Ty1-DR6 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

492192

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.407

High

512427

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.407

High

628725

PHO84
Inorganic phosphate transporter PHO84

1

2

High-throughput

0.407

High

657272

URA7
CTP synthase 1

1

1

High-throughput

0.407

High

687465

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

695351

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.407

High

753925

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.407

High

770522

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.407

High

778789

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.407

High

817289

HLJ1
Protein HLJ1

1

4

High-throughput

0.407

High

859264

INO80
Chromatin-remodeling ATPase INO80

1

1

High-throughput

0.407

High

972438

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

972439

YE12B
Transposon Ty1-ER2 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

972441

YD11B
Transposon Ty1-DR1 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

972451

YB12B
Transposon Ty1-BR Gag-Pol polyprotein

1

6

High-throughput

0.407

High

972453

YD12B
Transposon Ty1-DR3 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

972443

AIM32
Altered inheritance of mitochondria protein 32

1

0

Small-scale

0.261

Low

524424

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

690795

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.249

Low

745835

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

634496

PEX34
Peroxisomal membrane protein PEX34

1

0

High-throughput

0.238

Low

972440

YMD8
Putative nucleotide-sugar transporter YMD8

1

0

High-throughput

0.238

Low

972446

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

0

High-throughput

0.238

Low

972450

GET3
ATPase GET3

1

0

High-throughput

0.238

Low

423480

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.232

Low

732354

YKH5
Uncharacterized protein YKL075C

1

0

High-throughput

0.232

Low

752964

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.232

Low

811437

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

860282

ORM1
Protein ORM1

1

0

High-throughput

0.232

Low

866128

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024