Protein: MAD1
Spindle assembly checkpoint component MAD1 (Mitotic arrest deficient protein 1)

Gene: MAD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P40957

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0006913 - nucleocytoplasmic transport
GO:0007094 - mitotic spindle assembly checkpoint signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778457

MAD2
Mitotic spindle checkpoint component MAD2

7

1

Small-scale

0.974

High

643040

BUB3
Cell cycle arrest protein BUB3

4

19

Small-scale

0.697

High

778458

BUB1
Checkpoint serine/threonine-protein kinase BUB1

3

15

Small-scale

0.674

High

778456

MAD1
Spindle assembly checkpoint component MAD1

1

17

High-throughput

0.656

High

640847

CDC20
APC/C activator protein CDC20

2

16

Small-scale

0.590

High

778475

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.570

High

778476

HDA2
HDA1 complex subunit 2

2

0

High-throughput

0.570

High

778473

NUP53
Nucleoporin NUP53

2

0

Small-scale

0.569

High

778469

CDC14
Tyrosine-protein phosphatase CDC14

1

12

Small-scale

0.561

High

775737

DSN1
Kinetochore-associated protein DSN1

2

0

Small-scale

0.559

High

491506

HSP71
Heat shock protein SSA1

2

10

High-throughput

0.552

High

698719

ORC2
Origin recognition complex subunit 2

1

2

Small-scale

0.541

High

511650

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.536

High

700777

SMC1
Structural maintenance of chromosomes protein 1

1

10

High-throughput

0.508

High

778468

MPS1
Serine/threonine-protein kinase MPS1

1

20

Small-scale

0.501

High

766792

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.486

High

410003

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.481

High

560692

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.481

High

703652

PRS6A
26S proteasome regulatory subunit 6A

1

4

High-throughput

0.481

High

706019

NIP80
Protein NIP100

1

20

High-throughput

0.481

High

710775

CASP
Protein CASP

1

19

High-throughput

0.481

High

728703

BDF1
Bromodomain-containing factor 1

1

16

High-throughput

0.481

High

778460

GZF3
Protein GZF3

1

1

High-throughput

0.481

High

778470

PRS8
26S proteasome regulatory subunit 8 homolog

1

2

High-throughput

0.481

High

778471

SPP1
COMPASS component SPP1

1

4

High-throughput

0.481

High

778472

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

4

High-throughput

0.481

High

778477

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

2

High-throughput

0.481

High

662478

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

688281

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

702674

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

778465

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.460

High

778478

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.460

High

733444

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

778464

SP105
Spindle pole body component SPC105

1

0

Small-scale

0.458

High

778466

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.458

High

778474

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.458

High

366440

HSP82
ATP-dependent molecular chaperone HSP82

1

7

High-throughput

0.445

High

494197

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

633300

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

680783

HS104
Heat shock protein 104

1

3

High-throughput

0.445

High

694881

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

754483

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

761241

CAJ1
Protein CAJ1

1

5

High-throughput

0.445

High

678182

ZIP1
Synaptonemal complex protein ZIP1

1

16

High-throughput

0.439

High

688895

SMY1
Kinesin-related protein SMY1

1

16

High-throughput

0.439

High

690216

CDC3
Cell division control protein 3

1

6

High-throughput

0.439

High

731055

YKT6
Synaptobrevin homolog YKT6

1

3

High-throughput

0.439

High

731323

DYHC
Dynein heavy chain, cytoplasmic

1

5

High-throughput

0.439

High

755144

LAM4
Membrane-anchored lipid-binding protein LAM4

1

2

High-throughput

0.439

High

756513

KOG1
Target of rapamycin complex 1 subunit KOG1

1

14

High-throughput

0.439

High

767510

TSC11
Target of rapamycin complex 2 subunit TSC11

1

4

High-throughput

0.439

High

778461

GCN20
Protein GCN20

1

2

High-throughput

0.439

High

778463

MDV1
Mitochondrial division protein 1

1

18

High-throughput

0.439

High

778467

AP18B
Clathrin coat assembly protein AP180B

1

7

High-throughput

0.439

High

333819

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.407

High

563964

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.251

Low

746735

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

778462

STB2
Protein STB2

1

0

High-throughput

0.251

Low

778479

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.251

Low

778480

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

778459

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024