Protein: HLX
H2.0-like homeobox protein (Homeobox protein HB24) (Homeobox protein HLX1)

Gene: HLX
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q14774

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001889 - liver development
GO:0005634 - nucleus
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

326331

SCAF4
SR-related and CTD-associated factor 4

2

20

High-throughput

0.628

High

625381

CSK22
Casein kinase II subunit alpha'

2

18

High-throughput

0.628

High

997717

CSK21
Casein kinase II subunit alpha

2

12

High-throughput

0.628

High

1047907

TLE2
Transducin-like enhancer protein 2

2

20

High-throughput

0.628

High

1047973

TLE3
Transducin-like enhancer protein 3

2

20

High-throughput

0.628

High

1061697

TLE5
TLE family member 5

2

20

High-throughput

0.628

High

1132181

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

3

High-throughput

0.628

High

1047817

TLE1
Transducin-like enhancer protein 1

2

20

High-throughput

0.611

High

1048157

TLE4
Transducin-like enhancer protein 4

2

20

High-throughput

0.611

High

288087

FOXH1
Forkhead box protein H1

2

20

High-throughput

0.606

High

505561

ATX1L
Ataxin-1-like

2

13

High-throughput

0.606

High

1132184

ARK2N
Protein ARK2N

2

0

High-throughput

0.602

High

1132180

CE120
Centrosomal protein of 120 kDa

2

1

High-throughput

0.574

High

70208

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.553

High

1132175

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

3

High-throughput

0.553

High

1132179

DTX2
Probable E3 ubiquitin-protein ligase DTX2

2

5

High-throughput

0.553

High

1132182

LMO7
LIM domain only protein 7

1

2

High-throughput

0.536

High

1132187

ADT4
ADP/ATP translocase 4

1

0

High-throughput

0.513

High

701983

TMOD1
Tropomodulin-1

1

1

High-throughput

0.489

High

896238

PEX5
Peroxisomal targeting signal 1 receptor

1

9

High-throughput

0.489

High

1132186

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.489

High

1095634

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.481

High

606771

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

613039

EGR1
Early growth response protein 1

1

12

High-throughput

0.479

High

1132183

HDAC2
Histone deacetylase 2

1

10

High-throughput

0.479

High

1017635

PR20D
Proline-rich protein 20D

1

6

High-throughput

0.470

High

828773

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

1132174

SUZ12
Polycomb protein SUZ12

1

0

Small-scale

0.458

High

1132176

Q5JSZ1
TLE family member 4, transcriptional corepressor

1

20

High-throughput

0.445

High

1132177

Q5T3G3
TLE family member 1, transcriptional corepressor

1

20

High-throughput

0.445

High

1017699

PR20A
Proline-rich protein 20A

1

6

High-throughput

0.439

High

892292

SPS1
Selenide, water dikinase 1

2

0

High-throughput

0.328

High

1132185

MIEN1
Migration and invasion enhancer 1

2

0

High-throughput

0.316

High

1132188

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.316

High

996453

ACTS
Actin, alpha skeletal muscle

1

0

High-throughput

0.279

Low

1132178

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025