Protein: LIS1
Nuclear distribution protein PAC1 (Lissencephaly-1 homolog) (LIS-1) (nudF homolog)

Gene: LIS1, PAC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: P39946

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0005634 - nucleus
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

731315

DYHC
Dynein heavy chain, cytoplasmic

7

9

Small-scale

0.961

High

765462

LIS1
Nuclear distribution protein PAC1

5

17

Small-scale

0.919

High

765488

NDE1
Nuclear distribution protein nudE homolog 1

5

0

Small-scale

0.682

High

765472

UBC9
SUMO-conjugating enzyme UBC9

1

10

Small-scale

0.621

High

765478

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

8

High-throughput

0.621

High

756248

KEL1
Kelch repeat-containing protein 1

2

10

High-throughput

0.595

High

748532

ARPC1
Actin-related protein 2/3 complex subunit 1

1

17

High-throughput

0.595

High

514561

BIK1
Nuclear fusion protein BIK1

2

8

Small-scale

0.584

High

765468

STU2
Protein STU2

2

6

Small-scale

0.584

High

679790

SWC3
SWR1-complex protein 3

2

0

High-throughput

0.570

High

748274

CENPU
Inner kinetochore subunit AME1

2

0

High-throughput

0.570

High

765470

NNF1
Kinetochore-associated protein NNF1

2

0

High-throughput

0.570

High

765479

UBC7
Ubiquitin-conjugating enzyme E2 7

1

20

High-throughput

0.528

High

765483

NSE5
Non-structural maintenance of chromosome element 5

1

0

High-throughput

0.518

High

419890

SNF1
Carbon catabolite-derepressing protein kinase

1

5

High-throughput

0.501

High

342724

ENO1
Enolase 1

1

4

High-throughput

0.500

High

411009

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

554653

HSP26
Heat shock protein 26

1

2

High-throughput

0.500

High

454340

TBA1
Tubulin alpha-1 chain

1

10

High-throughput

0.481

High

477295

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

18

Small-scale

0.481

High

605649

KIN3
Serine/threonine-protein kinase KIN3

1

19

High-throughput

0.481

High

622027

SSD1
Protein SSD1

1

1

High-throughput

0.481

High

623477

KPC1
Protein kinase C-like 1

1

13

High-throughput

0.481

High

703628

PRS6A
26S proteasome regulatory subunit 6A

1

11

High-throughput

0.481

High

707999

NUF2
Kinetochore protein NUF2

1

7

High-throughput

0.481

High

752792

SYSM
Serine--tRNA ligase, mitochondrial

1

4

High-throughput

0.481

High

756042

WSS1
DNA-dependent metalloprotease WSS1

1

1

Small-scale

0.481

High

759223

END3
Actin cytoskeleton-regulatory complex protein END3

1

6

High-throughput

0.481

High

765465

PFD2
Prefoldin subunit 2

1

6

High-throughput

0.481

High

765471

HMS2
Probable transcription factor HMS2

1

6

High-throughput

0.481

High

765473

PFD6
Prefoldin subunit 6

1

6

High-throughput

0.481

High

765475

NST1
Stress response protein NST1

1

20

High-throughput

0.481

High

765482

VPS60
Vacuolar protein-sorting-associated protein 60

1

7

High-throughput

0.481

High

765485

VPS20
Vacuolar protein sorting-associated protein 20

1

7

High-throughput

0.481

High

765489

ULS1
ATP-dependent helicase ULS1

1

18

Small-scale

0.481

High

765490

SRL2
Protein SRL2

1

1

High-throughput

0.481

High

765491

SIZ2
E3 SUMO-protein ligase SIZ2

1

2

Small-scale

0.481

High

765493

SMT3
Ubiquitin-like protein SMT3

1

3

Small-scale

0.481

High

765494

RLF2
Chromatin assembly factor 1 subunit p90

1

7

High-throughput

0.481

High

765492

RPN5
26S proteasome regulatory subunit RPN5

1

5

Small-scale

0.479

High

587855

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.460

High

727990

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.460

High

734060

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

746726

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

765464

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

765466

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

765476

NIS1
Protein NIS1

1

0

Small-scale

0.460

High

765477

DAD4
DASH complex subunit DAD4

1

0

High-throughput

0.460

High

765481

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

765484

ECM11
Protein ECM11

1

0

High-throughput

0.460

High

526786

CG13
G1/S-specific cyclin CLN3

1

6

High-throughput

0.457

High

334937

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

4

High-throughput

0.457

High

588094

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.457

High

765467

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

755137

LAM4
Membrane-anchored lipid-binding protein LAM4

1

1

High-throughput

0.439

High

765480

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

14

High-throughput

0.437

High

765463

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.269

Low

765474

NNF2
Protein NNF2

1

0

High-throughput

0.265

Low

741299

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.251

Low

765469

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

765486

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

765487

FMP27
Protein FMP27, mitochondrial

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024