Protein: OTC
Ornithine carbamoyltransferase (EC 2.1.3.3) (Ornithine transcarbamylase) (OTCase)

Gene: OTC, ARG3
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P05150

Gene Ontology (top 5):
GO:0004585 - ornithine carbamoyltransferase activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006526 - arginine biosynthetic process
GO:0016597 - amino acid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

397602

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

341633

ARGI
Arginase

1

1

Small-scale

0.582

High

397562

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.500

High

397569

SRS2
ATP-dependent DNA helicase SRS2

1

1

High-throughput

0.500

High

397576

RFA1
Replication factor A protein 1

1

2

High-throughput

0.500

High

397579

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

4

High-throughput

0.500

High

397596

MLH1
DNA mismatch repair protein MLH1

1

1

High-throughput

0.500

High

397614

POLH
DNA polymerase eta

1

1

High-throughput

0.500

High

397623

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

3

High-throughput

0.500

High

397628

SMC6
Structural maintenance of chromosomes protein 6

1

3

High-throughput

0.500

High

397572

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.493

High

397568

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.479

High

397584

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.479

High

397593

TYDP1
Tyrosyl-DNA phosphodiesterase 1

1

0

High-throughput

0.479

High

397606

UBC13
Ubiquitin-conjugating enzyme E2 13

1

0

High-throughput

0.479

High

397607

MMS2
Ubiquitin-conjugating enzyme variant MMS2

1

0

High-throughput

0.479

High

397577

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

397595

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

397559

CDC7
Cell division control protein 7

1

7

High-throughput

0.464

High

397563

RAD2
DNA repair protein RAD2

1

2

High-throughput

0.457

High

397564

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

2

High-throughput

0.457

High

397565

PBS2
MAP kinase kinase PBS2

1

9

High-throughput

0.457

High

397573

PWP1
Periodic tryptophan protein 1

1

4

High-throughput

0.457

High

397575

DBF2
Cell cycle protein kinase DBF2

1

6

High-throughput

0.457

High

397578

RAD57
DNA repair protein RAD57

1

1

High-throughput

0.457

High

397581

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

1

High-throughput

0.457

High

397582

BUB3
Cell cycle arrest protein BUB3

1

3

High-throughput

0.457

High

397583

PSO2
DNA cross-link repair protein PSO2/SNM1

1

1

High-throughput

0.457

High

397587

MKK1
MAP kinase kinase MKK1/SSP32

1

7

High-throughput

0.457

High

397589

PP2C3
Protein phosphatase 2C homolog 3

1

2

High-throughput

0.457

High

397599

RFC2
Replication factor C subunit 2

1

2

High-throughput

0.457

High

397600

PRK1
Actin-regulating kinase PRK1

1

2

High-throughput

0.457

High

397603

BBC1
Myosin tail region-interacting protein MTI1

1

3

High-throughput

0.457

High

397605

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

7

High-throughput

0.457

High

397611

FAP1
FKBP12-associated protein 1

1

1

High-throughput

0.457

High

397613

WDR59
Maintenance of telomere capping protein 5

1

6

High-throughput

0.457

High

397616

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.457

High

397617

SEC13
Protein transport protein SEC13

1

3

High-throughput

0.457

High

397618

ITT1
E3 ubiquitin-protein ligase ITT1

1

2

High-throughput

0.457

High

397620

FAR10
Factor arrest protein 10

1

1

High-throughput

0.457

High

397624

PIB1
E3 ubiquitin-protein ligase PIB1

1

1

High-throughput

0.457

High

397626

PSH1
RING finger protein PSH1

1

1

High-throughput

0.457

High

397627

RAD59
DNA repair protein RAD59

1

2

High-throughput

0.457

High

365525

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

397566

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

397585

HS104
Heat shock protein 104

1

2

High-throughput

0.445

High

397598

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

397622

NCS1
Calcium-binding protein NCS-1

1

0

High-throughput

0.438

High

397588

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.437

High

397594

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

397609

CWC24
Pre-mRNA-splicing factor CWC24

1

1

High-throughput

0.437

High

397608

YG5B
Uncharacterized RNA-binding protein YGR250C

1

0

High-throughput

0.269

Low

397560

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.261

Low

397561

RAD7
DNA repair protein RAD7

1

0

High-throughput

0.261

Low

397567

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.261

Low

397570

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.261

Low

397571

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.261

Low

397574

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.261

Low

397580

PWP2
Periodic tryptophan protein 2

1

0

High-throughput

0.261

Low

397586

ARP2
Actin-related protein 2

1

0

High-throughput

0.261

Low

397590

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.261

Low

397591

MMS4
Crossover junction endonuclease MMS4

1

0

High-throughput

0.261

Low

397592

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.261

Low

397597

FHL1
Pre-rRNA-processing protein FHL1

1

0

High-throughput

0.261

Low

397601

SKP2
F-box protein SKP2

1

0

High-throughput

0.261

Low

397610

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.261

Low

397612

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.261

Low

397615

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.261

Low

397619

SML1
Ribonucleotide reductase inhibitor protein SML1

1

0

High-throughput

0.261

Low

397625

DDC1
DNA damage checkpoint protein 1

1

0

High-throughput

0.261

Low

397621

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

397604

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024