Protein: IF2
Translation initiation factor IF-2

Gene: IF2, infB
Organism: Escherichia coli K-12
Interactions: 54
UniProt ID: P0A705

Gene Ontology (top 5):
GO:0003743 - translation initiation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

491437

RL6
Large ribosomal subunit protein uL6

1

2

High-throughput

0.691

High

491434

NUSA
Transcription termination/antitermination protein NusA

2

2

High-throughput

0.612

High

365801

RPOD
RNA polymerase sigma factor RpoD

2

3

High-throughput

0.588

High

473243

DNAJ
Chaperone protein DnaJ

2

9

High-throughput

0.588

High

491438

IBPA
Small heat shock protein IbpA

2

3

High-throughput

0.588

High

491440

HELD
DNA helicase IV

2

4

High-throughput

0.588

High

491452

RLMN
Dual-specificity RNA methyltransferase RlmN

2

5

High-throughput

0.588

High

490795

GREA
Transcription elongation factor GreA

1

2

High-throughput

0.536

High

491418

RS5
Small ribosomal subunit protein uS5

1

8

High-throughput

0.536

High

491422

YEEN
Probable transcriptional regulatory protein YeeN

1

5

High-throughput

0.536

High

491429

KPYK1
Pyruvate kinase I

1

3

High-throughput

0.536

High

491433

FLIA
RNA polymerase sigma factor FliA

1

3

High-throughput

0.536

High

491436

SSPB
Stringent starvation protein B

1

1

High-throughput

0.536

High

491446

RHLE
ATP-dependent RNA helicase RhlE

1

4

High-throughput

0.536

High

491453

CSPB
Cold shock-like protein CspB

1

2

High-throughput

0.536

High

491456

UUP
ATP-binding protein Uup

1

8

High-throughput

0.536

High

491416

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

491427

EBGC
Evolved beta-galactosidase subunit beta

1

0

High-throughput

0.513

High

491430

YGFZ
tRNA-modifying protein YgfZ

1

0

High-throughput

0.513

High

491431

ENTB
Enterobactin synthase component B

1

0

High-throughput

0.513

High

491432

ARTM
Arginine ABC transporter permease protein ArtM

1

0

High-throughput

0.513

High

491449

YBIB
Uncharacterized protein YbiB

1

0

High-throughput

0.513

High

491461

LSRK
Autoinducer-2 kinase

1

0

High-throughput

0.513

High

491420

SUCC
Succinate--CoA ligase [ADP-forming] subunit beta

1

6

High-throughput

0.500

High

491441

KPYK2
Pyruvate kinase II

1

3

High-throughput

0.500

High

491442

SYD
Aspartate--tRNA ligase

1

10

High-throughput

0.500

High

491455

ADHP
Alcohol dehydrogenase, propanol-preferring

1

2

High-throughput

0.489

High

491460

HYFR
DNA-binding transcriptional activator HyfR

1

2

High-throughput

0.489

High

491462

MHPR
DNA-binding transcriptional activator MhpR

1

4

High-throughput

0.489

High

480524

GRPE
Protein GrpE

1

4

High-throughput

0.484

High

490989

DNAK
Chaperone protein DnaK

1

8

High-throughput

0.484

High

491419

SSRP
SsrA-binding protein

1

1

High-throughput

0.484

High

491423

RL13
Large ribosomal subunit protein uL13

1

7

High-throughput

0.484

High

491450

METN
Methionine import ATP-binding protein MetN

1

12

High-throughput

0.484

High

491451

RAVA
Regulatory ATPase RavA

1

4

High-throughput

0.484

High

491459

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.484

High

491421

TIG
Trigger factor

1

0

High-throughput

0.479

High

491426

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.479

High

491425

EXBB
Biopolymer transport protein ExbB

1

1

High-throughput

0.479

High

491435

GCH1L
GTP cyclohydrolase 1 type 2 homolog

1

1

High-throughput

0.479

High

491444

PHOP
Transcriptional regulatory protein PhoP

1

1

High-throughput

0.479

High

490771

RSMG
Ribosomal RNA small subunit methyltransferase G

1

0

High-throughput

0.464

High

491417

RL33
Large ribosomal subunit protein bL33

1

0

High-throughput

0.464

High

491424

ACCA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

1

0

High-throughput

0.464

High

491439

ILVG
Acetolactate synthase isozyme 2 large subunit

1

1

High-throughput

0.407

High

365891

PPB
Alkaline phosphatase

2

0

High-throughput

0.319

High

491428

YECA
Uncharacterized protein YecA

1

0

High-throughput

0.279

Low

491443

ARPA
Ankyrin repeat protein A

1

0

High-throughput

0.279

Low

491447

RODZ
Cytoskeleton protein RodZ

1

0

High-throughput

0.279

Low

491457

YEDJ
Uncharacterized protein YedJ

1

0

High-throughput

0.279

Low

491458

FLIJ
Flagellar FliJ protein

1

0

High-throughput

0.279

Low

491445

RIBD
Riboflavin biosynthesis protein RibD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase

1

0

High-throughput

0.253

Low

491448

HOLA
DNA polymerase III subunit delta

1

0

High-throughput

0.253

Low

491454

BCSG
Cellulose biosynthesis protein BcsG

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025