Protein: CCA
Multifunctional CCA protein [Includes: CCA-adding enzyme (EC 2.7.7.72) (CCA tRNA nucleotidyltransferase) (tRNA CCA-pyrophosphorylase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA nucleotidyltransferase) (tRNA-NT); 2'-nucleotidase (EC 3.1.3.-); 2',3'-cyclic phosphodiesterase (EC 3.1.4.-); Phosphatase (EC 3.1.3.-)]

Gene: CCA
Organism: Escherichia coli K-12
Interactions: 25
UniProt ID: P06961

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0000287 - magnesium ion binding
GO:0001680 - tRNA 3'-terminal CCA addition
GO:0004112 - cyclic-nucleotide phosphodiesterase activity
GO:0004810 - CCA tRNA nucleotidyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449899

PUR7
Phosphoribosylaminoimidazole-succinocarboxamide synthase

2

0

High-throughput

0.563

High

395057

DNAA
Chromosomal replication initiator protein DnaA

1

0

High-throughput

0.513

High

449896

HSLU
ATP-dependent protease ATPase subunit HslU

1

0

High-throughput

0.513

High

449897

DTD
D-aminoacyl-tRNA deacylase

1

0

High-throughput

0.513

High

449901

RS9
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

449904

BTUR
Corrinoid adenosyltransferase

1

0

High-throughput

0.513

High

449910

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

449911

RNR
Ribonuclease R

1

1

High-throughput

0.489

High

449916

RL2
Large ribosomal subunit protein uL2

1

1

High-throughput

0.489

High

449909

EFTU2
Elongation factor Tu 2

1

1

High-throughput

0.457

High

449908

EFTU1
Elongation factor Tu 1

1

1

High-throughput

0.445

High

449895

PFLB
Formate acetyltransferase 1

2

0

High-throughput

0.318

High

449898

FABH
Beta-ketoacyl-[acyl-carrier-protein] synthase III

1

0

High-throughput

0.279

Low

449900

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.279

Low

449907

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.279

Low

449912

MUKE
Chromosome partition protein MukE

1

0

High-throughput

0.279

Low

449913

HTRE
Outer membrane usher protein HtrE

1

0

High-throughput

0.279

Low

449914

PTKB
PTS system galactitol-specific EIIB component

1

0

High-throughput

0.279

Low

449915

YGJK
Glucosidase YgjK

1

0

High-throughput

0.279

Low

449917

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.279

Low

449918

MAO2
NADP-dependent malic enzyme

1

0

High-throughput

0.279

Low

449902

YEEN
Probable transcriptional regulatory protein YeeN

1

0

High-throughput

0.253

Low

449903

RPOB
DNA-directed RNA polymerase subunit beta

1

0

High-throughput

0.253

Low

449905

CSPA
Cold shock protein CspA

1

0

High-throughput

0.253

Low

449906

IOJAP
Ribosomal silencing factor RsfS

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025