Protein: MED20
Mediator of RNA polymerase II transcription subunit 20 (Hyper-recombination suppressor protein 2) (Mediator complex subunit 20) (Suppressor of RNA polymerase B 2)

Gene: MED20, SRB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P34162

Gene Ontology (top 5):
GO:0001094 - TFIID-class transcription factor complex binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0010688 - negative regulation of ribosomal protein gene transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

693526

MED17
Mediator of RNA polymerase II transcription subunit 17

18

0

Small-scale

0.935

High

693913

MED18
Mediator of RNA polymerase II transcription subunit 18

14

0

Small-scale

0.933

High

710260

MED8
Mediator of RNA polymerase II transcription subunit 8

9

0

Small-scale

0.715

High

581350

MED14
Mediator of RNA polymerase II transcription subunit 14

7

0

Small-scale

0.709

High

557984

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.699

High

586285

MED15
Mediator of RNA polymerase II transcription subunit 15

6

0

Small-scale

0.696

High

710277

MED7
Mediator of RNA polymerase II transcription subunit 7

6

0

Small-scale

0.696

High

693583

MED22
Mediator of RNA polymerase II transcription subunit 22

5

0

Small-scale

0.682

High

710280

MED2
Mediator of RNA polymerase II transcription subunit 2

5

0

Small-scale

0.676

High

710271

MED5
Mediator of RNA polymerase II transcription subunit 5

4

0

Small-scale

0.657

High

710262

MED6
Mediator of RNA polymerase II transcription subunit 6

4

0

Small-scale

0.638

High

704143

MED9
Mediator of RNA polymerase II transcription subunit 9

3

0

Small-scale

0.622

High

626021

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.616

High

710261

MED31
Mediator of RNA polymerase II transcription subunit 31

3

0

High-throughput

0.616

High

368727

GCN4
General control transcription factor GCN4

3

0

Small-scale

0.613

High

710267

MED3
Mediator of RNA polymerase II transcription subunit 3

3

0

Small-scale

0.597

High

686837

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.585

High

710282

MED1
Mediator of RNA polymerase II transcription subunit 1

2

0

High-throughput

0.585

High

526987

TBP
TATA-box-binding protein

2

0

Small-scale

0.576

High

710257

DEF1
RNA polymerase II degradation factor 1

2

0

High-throughput

0.576

High

710276

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.576

High

710284

MED4
Mediator of RNA polymerase II transcription subunit 4

2

0

High-throughput

0.576

High

710285

MED11
Mediator of RNA polymerase II transcription subunit 11

2

0

High-throughput

0.576

High

710269

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

0

Small-scale

0.569

High

710259

TAF5
Transcription initiation factor TFIID subunit 5

2

0

Small-scale

0.563

High

710283

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.563

High

355434

H2B1
Histone H2B.1

2

0

Small-scale

0.560

High

710268

T2FB
Transcription initiation factor IIF subunit beta

2

0

Small-scale

0.559

High

661818

TF2B
Transcription initiation factor IIB

2

0

Small-scale

0.547

High

587836

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.513

High

710275

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.513

High

630175

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.493

High

691310

NGG1
Chromatin-remodeling complexes subunit NGG1

1

0

Small-scale

0.493

High

710266

HAT2
Histone acetyltransferase type B subunit 2

1

0

High-throughput

0.493

High

710278

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.493

High

356382

H4
Histone H4

1

0

Small-scale

0.480

High

375343

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.480

High

381539

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.458

High

710256

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.458

High

710263

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.458

High

710264

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

High-throughput

0.458

High

710270

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.458

High

710273

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

710281

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

450000

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

490800

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

493597

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

510800

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

710272

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

412455

KIN28
Serine/threonine-protein kinase KIN28

1

0

Small-scale

0.426

High

710258

T2EB
Transcription initiation factor IIE subunit beta

1

0

Small-scale

0.426

High

710265

LAA1
AP-1 accessory protein LAA1

2

0

High-throughput

0.305

High

710274

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

592866

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low

710279

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024