Protein: SENP6
Sentrin-specific protease 6 (EC 3.4.22.-) (SUMO-1-specific protease 1) (Sentrin/SUMO-specific protease SENP6)

Gene: SENP6
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q9GZR1

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902747

SUMO2
Small ubiquitin-related modifier 2

2

20

Small-scale

0.778

High

1326248

PRP19
Pre-mRNA-processing factor 19

4

8

High-throughput

0.699

High

928190

SUMO1
Small ubiquitin-related modifier 1

1

20

Small-scale

0.647

High

360387

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

8

High-throughput

0.640

High

1044698

FHL3
Four and a half LIM domains protein 3

2

0

High-throughput

0.585

High

668962

PML
Protein PML

2

7

High-throughput

0.584

High

1326250

RUVB2
RuvB-like 2

2

2

Small-scale

0.584

High

435171

SP1
Transcription factor Sp1

1

2

High-throughput

0.561

High

1326249

EXO1
Exonuclease 1

1

0

Small-scale

0.537

High

1272597

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

1022447

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

0

High-throughput

0.518

High

347841

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

387467

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

455846

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.479

High

721386

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

802495

ATRX
Transcriptional regulator ATRX

1

3

Small-scale

0.479

High

828369

CENPA
Histone H3-like centromeric protein A

1

6

High-throughput

0.479

High

918668

H2B1C
Histone H2B type 1-C/E/F/G/I

1

5

High-throughput

0.479

High

935214

H31
Histone H3.1

1

6

High-throughput

0.479

High

952610

H33
Histone H3.3

1

6

High-throughput

0.479

High

980869

TLE3
Transducin-like enhancer protein 3

1

7

High-throughput

0.479

High

1027246

CBX3
Chromobox protein homolog 3

1

7

High-throughput

0.479

High

1221718

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1222562

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

1244477

NUP43
Nucleoporin Nup43

1

10

High-throughput

0.479

High

1246169

COP1
E3 ubiquitin-protein ligase COP1

1

9

High-throughput

0.479

High

1273481

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.479

High

1288295

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

6

High-throughput

0.479

High

1303724

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.479

High

1326242

RN146
E3 ubiquitin-protein ligase RNF146

1

2

Small-scale

0.479

High

1326244

NLE1
Notchless protein homolog 1

1

5

High-throughput

0.479

High

1326246

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1326247

NUP50
Nuclear pore complex protein Nup50

1

3

High-throughput

0.479

High

1326251

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

484392

SCHI1
Schwannomin-interacting protein 1

1

0

High-throughput

0.458

High

1200645

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1326243

FANCI
Fanconi anemia group I protein

1

0

Small-scale

0.458

High

1326245

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1326241

ZDBF2
DBF4-type zinc finger-containing protein 2

2

0

High-throughput

0.319

High

537573

PA2GA
Phospholipase A2, membrane associated

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024