Protein: PT1
Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system, enzyme I)

Gene: PT1, ptsI
Organism: Escherichia coli K-12
Interactions: 17
UniProt ID: P08839

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0008965 - phosphoenolpyruvate-protein phosphotransferase activity
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0015764 - N-acetylglucosamine transport
GO:0016301 - kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476457

PTHP
Phosphocarrier protein HPr

4

1

Small-scale

0.888

High

476454

PT1
Phosphoenolpyruvate-protein phosphotransferase

2

1

Small-scale

0.768

High

476464

HELD
DNA helicase IV

2

0

High-throughput

0.585

High

476459

PURR
HTH-type transcriptional repressor PurR

1

1

High-throughput

0.536

High

456075

CHEB
Protein-glutamate methylesterase/protein-glutamine glutaminase

1

0

High-throughput

0.513

High

473234

DNAJ
Chaperone protein DnaJ

1

0

High-throughput

0.513

High

476462

FTSY
Signal recognition particle receptor FtsY

1

0

High-throughput

0.513

High

476465

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.513

High

476458

GLCC
Glc operon transcriptional activator

1

1

High-throughput

0.494

High

476467

NAGK
N-acetyl-D-glucosamine kinase

1

1

High-throughput

0.489

High

476455

ACKA
Acetate kinase

1

0

Small-scale

0.458

High

476456

GREA
Transcription elongation factor GreA

1

0

High-throughput

0.426

High

476463

BGLG
Cryptic beta-glucoside bgl operon antiterminator

1

0

Small-scale

0.288

High

476461

FIMZ
Fimbriae Z protein

1

0

High-throughput

0.282

High

476460

ENTC
Isochorismate synthase EntC

1

0

High-throughput

0.279

Low

476466

DGCZ
Diguanylate cyclase DgcZ

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025