Protein: AFT1
Iron-regulated transcriptional activator AFT1 (Activator of iron transcription protein 1)

Gene: AFT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 89
UniProt ID: P22149

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605258

GLRX3
Monothiol glutaredoxin-3

7

2

Small-scale

0.748

High

605220

GLRX4
Monothiol glutaredoxin-4

5

2

Small-scale

0.724

High

605228

CENPL
Inner kinetochore subunit IML3

3

0

Small-scale

0.621

High

605204

AFT1
Iron-regulated transcriptional activator AFT1

2

1

Small-scale

0.614

High

514146

NHP6A
Non-histone chromosomal protein 6A

2

0

Small-scale

0.603

High

539914

RAD9
DNA repair protein RAD9

1

0

Small-scale

0.537

High

542099

CYC8
General transcriptional corepressor CYC8

1

0

Small-scale

0.537

High

605215

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.537

High

605239

MSN5
Protein MSN5

1

0

Small-scale

0.529

High

605256

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.513

High

605233

YAP5
AP-1-like transcription factor YAP5

1

0

High-throughput

0.486

High

605246

ZPR1
Zinc finger chaperone ZPR1

1

0

High-throughput

0.486

High

605214

IMB3
Importin subunit beta-3

1

0

Small-scale

0.480

High

605210

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

605253

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

1

Small-scale

0.479

High

565142

CBF1
Centromere-binding protein 1

1

0

Small-scale

0.460

High

605240

NBP35
Cytosolic Fe-S cluster assembly factor NBP35

1

0

Small-scale

0.460

High

605271

NBP2
NAP1-binding protein 2

1

0

High-throughput

0.460

High

586260

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

Small-scale

0.458

High

605224

MAC1
Metal-binding activator 1

1

0

Small-scale

0.458

High

605225

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

605229

CENPN
Inner kinetochore subunit CHL4

1

0

Small-scale

0.458

High

605255

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.458

High

605260

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

605268

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

605270

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

605263

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

1

High-throughput

0.457

High

490355

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

493215

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

510277

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

603275

SNF2
Transcription regulatory protein SNF2

1

2

High-throughput

0.445

High

605206

MCM3
DNA replication licensing factor MCM3

1

2

High-throughput

0.445

High

605209

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.445

High

605211

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.445

High

605212

MCM5
Minichromosome maintenance protein 5

1

2

High-throughput

0.445

High

605213

BTAF1
TATA-binding protein-associated factor MOT1

1

3

High-throughput

0.445

High

605217

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

605218

SWI3
SWI/SNF complex subunit SWI3

1

2

High-throughput

0.445

High

605219

STH1
Nuclear protein STH1/NPS1

1

2

High-throughput

0.445

High

605222

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

1

High-throughput

0.445

High

605223

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.445

High

605227

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

1

High-throughput

0.445

High

605234

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

1

High-throughput

0.445

High

605235

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

High-throughput

0.445

High

605242

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.445

High

605243

INO80
Chromatin-remodeling ATPase INO80

1

1

High-throughput

0.445

High

605248

SNF12
Transcription regulatory protein SNF12

1

1

High-throughput

0.445

High

605254

ADA2
Transcriptional adapter 2

1

2

High-throughput

0.445

High

605259

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

605262

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

605266

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

3

High-throughput

0.445

High

605272

ARP8
Actin-like protein ARP8

1

1

High-throughput

0.445

High

605273

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

605274

H2AZ
Histone H2A.Z

1

1

High-throughput

0.445

High

605261

MYO5
Myosin-5

1

0

High-throughput

0.438

High

355782

H2B2
Histone H2B.2

1

0

High-throughput

0.426

High

356253

H4
Histone H4

1

0

High-throughput

0.426

High

392296

H2A2
Histone H2A.2

1

0

High-throughput

0.426

High

420591

SPT3
Protein SPT3

1

0

High-throughput

0.426

High

452072

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.426

High

526948

TBP
TATA-box-binding protein

1

0

High-throughput

0.426

High

577128

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

0

High-throughput

0.426

High

581335

MED14
Mediator of RNA polymerase II transcription subunit 14

1

0

High-throughput

0.426

High

605205

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.426

High

605207

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

605208

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.426

High

605216

NGG1
Chromatin-remodeling complexes subunit NGG1

1

0

High-throughput

0.426

High

605226

TAF5
Transcription initiation factor TFIID subunit 5

1

0

High-throughput

0.426

High

605230

SPT8
Transcription factor SPT8

1

0

High-throughput

0.426

High

605232

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.426

High

605237

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.426

High

605238

SPT20
Transcription factor SPT20

1

0

High-throughput

0.426

High

605241

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.426

High

605244

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.426

High

605245

ENV11
Late endosome and vacuole interface protein 11

1

0

High-throughput

0.426

High

605247

H1
Histone H1

1

0

High-throughput

0.426

High

605249

ACT
Actin

1

0

High-throughput

0.426

High

605250

H3
Histone H3

1

0

High-throughput

0.426

High

605251

RAD25
General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2

1

0

High-throughput

0.426

High

605252

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

605257

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.426

High

605264

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

0

High-throughput

0.426

High

605265

EAF1
Chromatin modification-related protein EAF1

1

0

High-throughput

0.426

High

605267

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.426

High

605269

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.426

High

605231

SIT1
Siderophore iron transporter 1

2

0

Small-scale

0.330

High

605221

CACP
Carnitine O-acetyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

605236

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024