Protein: OPLA
5-oxoprolinase (EC 3.5.2.9) (5-oxo-L-prolinase) (5-OPase) (Pyroglutamase)

Gene: OPLA, OXP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 34
UniProt ID: P28273

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006749 - glutathione metabolic process
GO:0017168 - 5-oxoprolinase (ATP-hydrolyzing) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701643

HS104
Heat shock protein 104

2

0

High-throughput

0.576

High

523255

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.571

High

701650

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

544049

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

701653

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.513

High

701656

SPC98
Spindle pole body component SPC98

1

0

High-throughput

0.493

High

701662

NBR9
Endonuclease NBR9

1

0

High-throughput

0.493

High

368612

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.479

High

452843

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.479

High

409978

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

434890

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

701645

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

701652

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

701655

HFM1
ATP-dependent DNA helicase MER3

1

0

Small-scale

0.458

High

701659

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

701661

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

701663

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

526091

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

670413

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

675770

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

701644

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

701651

DJP1
DnaJ-like protein 1

1

1

High-throughput

0.445

High

701658

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

392350

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

701647

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

701648

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.426

High

701649

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

701657

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

701660

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.426

High

701664

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

677311

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

701642

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

701654

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

701646

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025