Protein: PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) (Ketopantoate hydroxymethyltransferase) (KPHMT)

Gene: PANB
Organism: Escherichia coli K-12
Interactions: 18
UniProt ID: P31057

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003864 - 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0015940 - pantothenate biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724233

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

2

High-throughput

0.618

High

724234

PANC
Pantothenate synthetase

2

0

High-throughput

0.585

High

368810

SYI
Isoleucine--tRNA ligase

1

0

High-throughput

0.513

High

489358

ISCS
Cysteine desulfurase IscS

1

0

High-throughput

0.513

High

489440

CARA
Carbamoyl phosphate synthase small chain

1

0

High-throughput

0.513

High

494143

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

496806

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.513

High

496980

PFLA
Pyruvate formate-lyase 1-activating enzyme

1

0

High-throughput

0.513

High

493045

RL29
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

493263

RS10
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

493642

RS20
Small ribosomal subunit protein bS20

1

0

High-throughput

0.458

High

494973

TIG
Trigger factor

1

0

High-throughput

0.458

High

495087

TALB
Transaldolase B

1

0

High-throughput

0.458

High

497423

CSPC
Cold shock-like protein CspC

1

0

High-throughput

0.458

High

660201

PPSA
Phosphoenolpyruvate synthase

1

0

High-throughput

0.458

High

724235

PGM
Phosphoglucomutase

1

0

High-throughput

0.458

High

724236

NIMR
HTH-type transcriptional regulator NimR

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025