HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: Q9VKD5 (Q9VKD5)
Polycomb protein esc (Protein extra sex combs)
Gene: escl

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17210640
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~WD40
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 136 Dm			1 462
+	Hs
		845310 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		LIS1_HUMAN (207-462): 1.31e-54: 189: 16.19
+	Hs
		998776 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		TBL1R_HUMAN (9-288): 2.13e-50: 180: 14.87
+	Hs
		261420 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		TBL1X_HUMAN (4-288): 3.4e-50: 181: 15.62
+	Hs
		964837 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		WDR5_HUMAN (301-462): 3.76e-28: 115: 12.81
+	Hs
		964848 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		WDR5_HUMAN (301-462): 3.76e-28: 115: 12.81
+	Hs
		964981 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		WDR5_HUMAN (301-462): 3.76e-28: 115: 12.81
+	Hs
		998532 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		DAW1_HUMAN (316-462): 2.26e-24: 106: 16.11
+	Hs
		285205 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		EED_HUMAN (287-462): 7.63e-09: 59.5: 12.64
+	Dm
		381700 H3_DROME (1-136): 6.24e-61: 185: 100.00		ESC_DROME (9-243): 2e-09: 61.5: 9.60
+	Hs
		285216 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		EED_HUMAN (287-462): 7.63e-09: 59.5: 12.64
+	Hs
		285313 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		EED_HUMAN (287-462): 7.63e-09: 59.5: 12.64
+	Sc
		779302 CENPA_YEAST (18-134): 2.58e-43: 143: 56.67		COPA_YEAST (331-462): 2.33e-20: 96.5: 17.91