Protein: GUAA
GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) (GMP synthetase) (Glutamine amidotransferase)

Gene: GUAA, GUA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P38625

Gene Ontology (top 5):
GO:0003921 - GMP synthase activity
GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006177 - GMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

392658

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.584

High

800875

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

544711

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.571

High

800874

SSB2
Ribosome-associated molecular chaperone SSB2

2

13

High-throughput

0.552

High

800880

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

744222

GLRX4
Monothiol glutaredoxin-4

1

2

Small-scale

0.481

High

800884

GLRX3
Monothiol glutaredoxin-3

1

2

Small-scale

0.481

High

435056

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

435930

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

455032

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

512977

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

518279

IF4A
ATP-dependent RNA helicase eIF4A

1

5

High-throughput

0.479

High

579314

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

646387

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

670649

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

674590

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

726985

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

747828

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

750643

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

800871

RPN10
26S proteasome regulatory subunit RPN10

1

2

High-throughput

0.479

High

800872

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

800876

MPS3
Spindle pole body assembly component MPS3

1

2

High-throughput

0.479

High

800877

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

800881

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

800883

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.479

High

800885

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

800888

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

800892

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.479

High

518007

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.457

High

523804

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

800882

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.445

High

558695

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.437

High

706976

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

734953

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

794962

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

800870

RPN1
26S proteasome regulatory subunit RPN1

1

5

High-throughput

0.437

High

800873

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

800879

HST2
NAD-dependent protein deacetylase HST2

1

6

High-throughput

0.437

High

800886

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

800889

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

800890

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

454439

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

460968

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.279

Low

800878

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

800887

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

800891

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025