Protein: LTE1
Guanine nucleotide exchange factor LTE1 (Low temperature essential protein 1)

Gene: LTE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 96
UniProt ID: P07866

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005933 - cellular bud
GO:0007265 - Ras protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376202

RAS2
Ras-like protein 2

4

20

Small-scale

0.902

High

460969

KEL1
Kelch repeat-containing protein 1

6

2

Small-scale

0.732

High

454675

KAPR
cAMP-dependent protein kinase regulatory subunit

1

2

High-throughput

0.691

High

364240

CDK1
Cyclin-dependent kinase 1

3

0

Small-scale

0.639

High

376173

RAS1
Ras-like protein 1

1

20

Small-scale

0.618

High

460940

RSR1
Ras-related protein RSR1

1

20

Small-scale

0.618

High

460958

2AAA
Protein phosphatase PP2A regulatory subunit A

2

0

High-throughput

0.595

High

460999

CDC14
Tyrosine-protein phosphatase CDC14

2

3

Small-scale

0.595

High

460970

TEM1
Protein TEM1

1

0

Small-scale

0.586

High

460966

CND2
Condensin complex subunit 2

2

0

Small-scale

0.585

High

461001

KIN4
Serine/threonine-protein kinase KIN4

2

2

Small-scale

0.579

High

367651

ENO1
Enolase 1

1

2

High-throughput

0.536

High

367857

ENO2
Enolase 2

1

2

High-throughput

0.536

High

368383

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.536

High

400049

PUR1
Amidophosphoribosyltransferase

1

3

High-throughput

0.536

High

460943

HXKG
Glucokinase-1

1

1

High-throughput

0.536

High

460957

BMH1
Protein BMH1

1

5

High-throughput

0.536

High

460959

PROB
Glutamate 5-kinase

1

1

High-throughput

0.536

High

461002

EMI2
Putative glucokinase-2

1

1

High-throughput

0.536

High

461003

DCE
Glutamate decarboxylase

1

3

High-throughput

0.536

High

460991

KEL2
Kelch repeat-containing protein 2

2

2

Small-scale

0.533

High

365527

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.513

High

439194

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.513

High

460931

OAT
Ornithine aminotransferase

1

0

High-throughput

0.513

High

460934

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.513

High

460939

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.513

High

460945

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.513

High

460954

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

460955

AROC
Chorismate synthase ARO2

1

0

High-throughput

0.513

High

460963

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.513

High

460965

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.513

High

460975

FHP
Flavohemoprotein

1

0

High-throughput

0.513

High

460979

FLO8
Transcriptional activator FLO8

1

0

High-throughput

0.513

High

460984

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.513

High

460992

RIB4
6,7-dimethyl-8-ribityllumazine synthase

1

0

High-throughput

0.513

High

460994

PNC1
Nicotinamidase

1

0

High-throughput

0.513

High

461004

PAL1
Protein PAL1

1

0

High-throughput

0.513

High

460942

SEC23
Protein transport protein SEC23

1

1

High-throughput

0.489

High

460950

NFS1
Cysteine desulfurase, mitochondrial

1

2

High-throughput

0.489

High

460981

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.489

High

460985

RS29A
Small ribosomal subunit protein uS14A

1

1

High-throughput

0.489

High

460986

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.489

High

453868

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.479

High

460941

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

460948

CG22
G2/mitotic-specific cyclin-2

1

1

Small-scale

0.479

High

460989

ASNS1
Asparagine synthetase [glutamine-hydrolyzing] 1

1

2

High-throughput

0.479

High

461000

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

4

High-throughput

0.479

High

461007

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

461008

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

460953

RFA2
Replication factor A protein 2

1

2

High-throughput

0.470

High

460983

MSL1
U2 small nuclear ribonucleoprotein B''

1

1

High-throughput

0.464

High

460961

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

460967

TPS3
Trehalose synthase complex regulatory subunit TPS3

1

0

High-throughput

0.458

High

460971

MET30
F-box protein MET30

1

4

High-throughput

0.457

High

460998

ZDS2
Protein ZDS2

1

3

High-throughput

0.457

High

392033

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

460938

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

460951

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

460962

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

460977

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

460980

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

460982

DJP1
DnaJ-like protein 1

1

1

High-throughput

0.445

High

460990

ASNS2
Asparagine synthetase [glutamine-hydrolyzing] 2

1

2

High-throughput

0.445

High

460996

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

461009

PMG3
Phosphoglycerate mutase 3

1

1

High-throughput

0.445

High

461010

HSP42
Heat shock protein 42

1

2

High-throughput

0.445

High

368549

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

460936

RS23B
Small ribosomal subunit protein uS12B

1

1

High-throughput

0.437

High

460947

SPT6
Transcription elongation factor SPT6

1

1

High-throughput

0.437

High

460956

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

460974

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

460978

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

460987

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

460988

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

460993

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

460995

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

460935

RS23A
Small ribosomal subunit protein uS12A

1

1

High-throughput

0.407

High

460949

SIS1
Protein SIS1

1

2

High-throughput

0.407

High

460973

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

460976

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

2

High-throughput

0.407

High

461006

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

3

High-throughput

0.407

High

361408

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.279

Low

460932

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

460933

HEM1
5-aminolevulinate synthase, mitochondrial

1

0

High-throughput

0.279

Low

460944

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.279

Low

460946

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.279

Low

460952

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.279

Low

460960

EF2
Elongation factor 2

1

0

High-throughput

0.279

Low

460964

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.279

Low

460968

GUAA
GMP synthase [glutamine-hydrolyzing]

1

0

High-throughput

0.279

Low

460997

EF3B
Elongation factor 3B

1

0

High-throughput

0.279

Low

461011

RAX2
Bud site selection protein RAX2

1

0

High-throughput

0.279

Low

461012

GLT1
Glutamate synthase [NADH]

1

0

High-throughput

0.279

Low

461005

TAZ
Tafazzin

1

0

High-throughput

0.269

Low

460937

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.249

Low

460972

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025