HitPredict - High confidence protein-protein interactions

Protein: DHB4
Peroxisomal multifunctional enzyme type 2 (MFE-2) (17-beta-hydroxysteroid dehydrogenase 4) (17-beta-HSD 4) (D-bifunctional protein) (DBP) (Multifunctional protein 2) (MFP-2) [Cleaved into: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.107) (EC 4.2.1.119) (3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase)]

Gene: DHB4, Hsd17b4
Organism: Mus musculus
Interactions: 14
UniProt ID: P51660

Gene Ontology (top 5):
GO:0000038 - very long-chain fatty acid metabolic process
GO:0003857 - (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
GO:0004300 - enoyl-CoA hydratase activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005739 - mitochondrion

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
906470	DHB4 Peroxisomal multifunctional enzyme type 2	2	17	High-throughput	0.754	High
906471	STING Stimulator of interferon genes protein	1	1	High-throughput	0.479	High
906475	CBAR1 CBY1-interacting BAR domain-containing protein 1	1	0	High-throughput	0.458	High
398179	CFAD Complement factor D	1	1	High-throughput	0.437	High
906472	Q3UJF1 Histone deacetylase	1	1	High-throughput	0.437	High
906474	SPOP Speckle-type POZ protein	1	4	High-throughput	0.437	High
906477	FNDC5 Fibronectin type III domain-containing protein 5	1	1	High-throughput	0.437	High
906478	BFAR Bifunctional apoptosis regulator	1	3	Small-scale	0.437	High
906479	EED Polycomb protein EED	1	2	High-throughput	0.437	High
906480	HDAC5 Histone deacetylase 5	1	1	High-throughput	0.407	High
660936	IRF8 Interferon regulatory factor 8	1	0	High-throughput	0.249	Low
906473	TEDC2 Tubulin epsilon and delta complex protein 2	1	0	High-throughput	0.249	Low
906476	TTC23 Tetratricopeptide repeat protein 23	1	0	High-throughput	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025