Protein: CASP1
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]

Gene: CASP1
Organism: Mus musculus
Interactions: 15
UniProt ID: P29452

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001819 - positive regulation of cytokine production
GO:0002221 - pattern recognition receptor signaling pathway
GO:0004197 - cysteine-type endopeptidase activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

712517

ASC
Apoptosis-associated speck-like protein containing a CARD

4

16

Small-scale

0.875

High

712512

NLRC4
NLR family CARD domain-containing protein 4

2

20

Small-scale

0.777

High

532185

IL1B
Interleukin-1 beta

2

7

Small-scale

0.737

High

712509

CASP4
Caspase-4

1

18

Small-scale

0.618

High

712515

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

20

Small-scale

0.618

High

712510

CASP7
Caspase-7

1

17

Small-scale

0.575

High

712516

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

20

Small-scale

0.515

High

602913

ENOA
Alpha-enolase

1

1

Small-scale

0.479

High

660918

IRF8
Interferon regulatory factor 8

1

3

High-throughput

0.479

High

712507

KSYK
Tyrosine-protein kinase SYK

1

7

Small-scale

0.479

High

712511

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

712513

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

6

Small-scale

0.479

High

712514

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.479

High

712518

PANX1
Pannexin-1 [Cleaved into: Caspase-activated pannexin-1

1

2

Small-scale

0.445

High

712508

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

3

Small-scale

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025