Protein: ISR1
Serine/threonine-protein kinase ISR1 (EC 2.7.11.1) (Inhibition of staurosporine resistance protein 1)

Gene: ISR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: Q06098

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004694 - eukaryotic translation initiation factor 2alpha kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

985882

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

0

High-throughput

0.656

High

565778

PHO85
Cyclin-dependent protein kinase PHO85

1

0

Small-scale

0.614

High

624645

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.614

High

633583

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.614

High

701812

YPT7
Ypt/Rab-type GTPase YPT7

1

0

High-throughput

0.614

High

750952

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

0

High-throughput

0.614

High

753479

RIM4
Meiotic activator RIM4

1

0

High-throughput

0.614

High

866765

CRZ1
Transcriptional regulator CRZ1

1

0

High-throughput

0.614

High

977553

GIR2
Protein GIR2

1

0

High-throughput

0.518

High

540161

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.513

High

605158

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.513

High

734867

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

758099

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.513

High

784937

PTE1
Peroxisomal acyl-coenzyme A thioester hydrolase 1

1

0

High-throughput

0.513

High

866055

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

976425

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.513

High

977442

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.513

High

985879

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.513

High

985880

PBP4
Protein PBP4

1

0

High-throughput

0.513

High

411250

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.480

High

549277

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.480

High

549762

STI1
Heat shock protein STI1

1

0

High-throughput

0.480

High

690343

CDC11
Cell division control protein 11

1

0

High-throughput

0.480

High

733030

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.480

High

733798

RNZ
Ribonuclease Z

1

0

High-throughput

0.480

High

777103

SYA
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

792372

YG4I
Uncharacterized GTP-binding protein YGR210C

1

0

High-throughput

0.480

High

793567

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

0

High-throughput

0.480

High

797232

BUD27
Bud site selection protein 27

1

0

High-throughput

0.480

High

812673

YJ9S
Uncharacterized protein YJR154W

1

0

High-throughput

0.480

High

832200

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.480

High

980339

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.480

High

431151

CDC4
Cell division control protein 4

1

0

Small-scale

0.458

High

979163

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

985881

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

423045

TOM70
Mitochondrial import receptor subunit TOM70

1

1

High-throughput

0.457

High

707934

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.438

High

769506

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

535994

CHS2
Chitin synthase 2

2

0

High-throughput

0.330

High

743837

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

972960

YP077
Uncharacterized protein YPL077C

1

0

High-throughput

0.261

Low


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Last updated: 15 Jul 2024