Protein: PCS1N
ProSAAS (Proprotein convertase subtilisin/kexin type 1 inhibitor) (Proprotein convertase 1 inhibitor) (pro-SAAS) [Cleaved into: KEP; Big SAAS (b-SAAS); Little SAAS (l-SAAS) (N-proSAAS); Big PEN-LEN (b-PEN-LEN) (SAAS CT(1-49)); PEN; Little LEN (l-LEN); Big LEN (b-LEN) (SAAS CT(25-40))]

Gene: PCS1N, PCSK1N
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q9UHG2

Gene Ontology (top 5):
GO:0002021 - response to dietary excess
GO:0004866 - endopeptidase inhibitor activity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005102 - signaling receptor binding
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

577476

PACA
Pituitary adenylate cyclase-activating polypeptide

3

0

High-throughput

0.638

High

448915

MMP10
Stromelysin-2

2

0

High-throughput

0.602

High

864030

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

1355455

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.513

High

1348812

PA2G3
Group 3 secretory phospholipase A2

1

0

High-throughput

0.493

High

1132855

DPS1
All trans-polyprenyl-diphosphate synthase PDSS1

1

1

High-throughput

0.489

High

1205675

DLP1
All trans-polyprenyl-diphosphate synthase PDSS2

1

1

High-throughput

0.489

High

1354120

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

2

0

High-throughput

0.328

High

1355456

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

2

0

High-throughput

0.328

High

1014811

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

2

0

High-throughput

0.318

High

988157

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.282

High

1126195

MTX3
Metaxin-3

1

0

High-throughput

0.279

Low

1243501

CHSTD
Carbohydrate sulfotransferase 13

1

0

High-throughput

0.279

Low

1336284

AGO4
Protein argonaute-4

1

0

High-throughput

0.279

Low

524597

LYL1
Protein lyl-1

1

0

High-throughput

0.249

Low

556996

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.249

Low

1044239

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024