HitPredict - High confidence protein-protein interactions

Protein: IAPP
Islet amyloid polypeptide (IAPP) (Amylin) (Diabetes-associated peptide) (DAP) (Insulinoma amyloid peptide)

Gene: IAPP
Organism: Homo sapiens
Interactions: 7
UniProt ID: P10997

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0005102 - signaling receptor binding
GO:0005179 - hormone activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
534549	IAPP Islet amyloid polypeptide	7	1	Small-scale	0.964	High
534550	IDE Insulin-degrading enzyme	1	1	Small-scale	0.568	High
534552	TRIP6 Thyroid receptor-interacting protein 6	1	0	High-throughput	0.493	High
452137	PDIA1 Protein disulfide-isomerase	1	0	Small-scale	0.458	High
534551	BACE1 Beta-secretase 1	1	1	Small-scale	0.445	High
534553	BACE2 Beta-secretase 2	1	1	Small-scale	0.407	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025