Protein: KHSE
Homoserine kinase (HK) (HSK) (EC 2.7.1.39)

Gene: KHSE, THR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: P17423

Gene Ontology (top 5):
GO:0004413 - homoserine kinase activity
GO:0005524 - ATP binding
GO:0009088 - threonine biosynthetic process
GO:0009092 - homoserine metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604416

KHSE
Homoserine kinase

2

0

High-throughput

0.729

High

525853

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

604447

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.479

High

604417

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

604420

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

604423

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

604432

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

604441

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

481467

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

522977

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

543731

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

604422

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

604434

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

604418

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

453407

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

604419

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

604424

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

604440

IMA1
Importin subunit alpha

2

0

High-throughput

0.323

High

604446

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.288

High

604431

TEM1
Protein TEM1

1

0

High-throughput

0.282

High

604438

DNM1
Dynamin-related protein DNM1

1

0

High-throughput

0.282

High

604437

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

604439

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.279

Low

604425

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.269

Low

604433

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

604421

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

604426

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.249

Low

604427

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

604428

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

604429

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

604430

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

604436

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

604442

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

604444

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

604445

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

604443

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.238

Low

604435

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025