Protein: CSN5
COP9 signalosome complex subunit 5 (EC 3.4.-.-)

Gene: CSN5, RRI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 17
UniProt ID: Q12468

Gene Ontology (top 5):
GO:0000338 - protein deneddylation
GO:0000747 - conjugation with cellular fusion
GO:0000754 - adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
GO:0004222 - metalloendopeptidase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1084672

RPN5
26S proteasome regulatory subunit RPN5

5

20

Small-scale

0.922

High

1084108

CDC53
Cell division control protein 53

2

14

Small-scale

0.757

High

1046495

CSI1
Cop9 signalosome-interactor 1

5

0

Small-scale

0.686

High

1044629

CSN9
COP9 signalosome complex subunit 9

5

0

Small-scale

0.684

High

825728

CSN11
Cop9 signalosome complex subunit 11

4

0

High-throughput

0.664

High

1084815

CSN10
COP9 signalosome complex subunit 10

4

0

Small-scale

0.664

High

509773

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

Small-scale

0.647

High

865882

CSN12
Cop9 signalosome complex subunit 12

2

0

Small-scale

0.600

High

910811

SKP1
Suppressor of kinetochore protein 1

1

2

High-throughput

0.515

High

865805

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

678765

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

1

High-throughput

0.457

High

546859

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

671277

SIS1
Protein SIS1

1

7

High-throughput

0.445

High

816486

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

820200

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

925164

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.445

High

828542

HACD
Very-long-chain

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025