Protein: PGPI
Pyroglutamyl-peptidase 1 (EC 3.4.19.3) (5-oxoprolyl-peptidase) (Pyroglutamyl aminopeptidase I) (PAP-I) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrrolidone-carboxylate peptidase)

Gene: PGPI, PGPEP1
Organism: Homo sapiens
Interactions: 16
UniProt ID: Q9NXJ5

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0016920 - pyroglutamyl-peptidase activity
GO:0030163 - protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

999420

HBB
Hemoglobin subunit beta

3

1

High-throughput

0.667

High

999691

HBA
Hemoglobin subunit alpha

3

1

High-throughput

0.667

High

852118

TNNT3
Troponin T, fast skeletal muscle

3

0

High-throughput

0.638

High

938680

ALR
FAD-linked sulfhydryl oxidase ALR

3

0

High-throughput

0.638

High

1390305

TRI11
E3 ubiquitin-protein ligase TRIM11

3

0

High-throughput

0.638

High

1381210

UB2E3
Ubiquitin-conjugating enzyme E2 E3

2

1

High-throughput

0.606

High

1392941

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1397298

UB2E2
Ubiquitin-conjugating enzyme E2 E2

2

1

High-throughput

0.553

High

1114456

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1452049

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

530458

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1199721

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1005977

GTF2I
General transcription factor II-I

3

0

High-throughput

0.347

High

1415491

SELO
Protein adenylyltransferase SelO, mitochondrial

3

0

High-throughput

0.347

High

715972

AQP1
Aquaporin-1

2

0

High-throughput

0.316

High

1132143

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025