Protein: FL2D
Pre-mRNA-splicing regulator female-lethal(2)D (dFL(2)D)

Gene: FL2D, fl(2)d
Organism: Drosophila melanogaster
Interactions: 99
UniProt ID: Q9Y091

Gene Ontology (top 5):
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0006397 - mRNA processing
GO:0007530 - sex determination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1489637

VIR
Protein virilizer

6

5

Small-scale

0.724

High

1487967

FLACC
Fl(2)d-associated complex component

4

19

Small-scale

0.694

High

1267577

NITO
RNA-binding protein spenito

4

2

Small-scale

0.672

High

1480962

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

3

7

Small-scale

0.633

High

1285495

MMD4
Modifier of mdg4

2

12

High-throughput

0.594

High

1484472

BOWEL
Protein bowel

2

5

High-throughput

0.594

High

1470333

MTA70
N(6)-adenosine-methyltransferase MT-A70-like protein

2

7

Small-scale

0.571

High

1485284

Q9VRY7
GH13213p

2

0

High-throughput

0.569

High

1489564

THOC5
THO complex subunit 5

2

0

High-throughput

0.569

High

1176430

SO
Protein sine oculis

1

3

Small-scale

0.552

High

1176893

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit 2

2

7

High-throughput

0.542

High

1440021

Q9I7J8
FI01424p

1

5

High-throughput

0.508

High

1458002

GRAU
Transcription factor grauzone

1

3

High-throughput

0.508

High

1473627

Q9VF74
Uncharacterized protein, isoform F

1

16

High-throughput

0.508

High

1485229

Q9VRX0
IP01005p

1

3

High-throughput

0.508

High

1475269

Q9VGU4
FI02822p

1

5

High-throughput

0.489

High

852541

CADF
Cofilin/actin-depolymerizing factor homolog

1

0

High-throughput

0.486

High

1465511

Q9V455
Importin subunit alpha

1

0

High-throughput

0.486

High

1468899

Q9VB23
Serine/threonine protein phosphatase 2A regulatory subunit

1

0

High-throughput

0.486

High

1269061

Q7KSP5
Lethal

1

6

High-throughput

0.481

High

847953

SNRPA
U1 small nuclear ribonucleoprotein A

1

5

Small-scale

0.479

High

1485521

Q9VSD6
D-Importin 7/RanBP7

1

2

Small-scale

0.479

High

1479038

Q9VK21
Kelch-like protein diablo

1

9

High-throughput

0.464

High

1490059

Q9W4I4
Helix loop helix protein 4C, isoform A

1

1

High-throughput

0.464

High

1344858

Q8SZN9
Lethal

1

7

High-throughput

0.457

High

1377932

Q95RW2
Crk oncogene, isoform B

1

20

High-throughput

0.451

High

304546

AUB
Protein aubergine

1

1

High-throughput

0.445

High

556832

PSA1
Proteasome subunit alpha type-1

1

3

Small-scale

0.445

High

611574

PSA4
Proteasome subunit alpha type-4

1

3

Small-scale

0.445

High

613706

JRA
Transcription factor Jra

1

3

Small-scale

0.445

High

662003

PP2A
Serine/threonine-protein phosphatase PP2A

1

7

Small-scale

0.445

High

911808

POLO
Serine/threonine-protein kinase polo

1

10

Small-scale

0.445

High

1060672

DDX49
Probable ATP-dependent RNA helicase Dbp45A

1

2

High-throughput

0.445

High

1064262

SQD
RNA-binding protein squid

1

1

High-throughput

0.445

High

1266649

Q7K4R6
LD26240p

1

2

High-throughput

0.445

High

1267684

Q7KMP8
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.445

High

1268437

PABP2
Polyadenylate-binding protein 2

1

2

Small-scale

0.445

High

1273722

Q7PLL3
Eukaryotic initiation factor 4B

1

1

Small-scale

0.445

High

1303417

Q8IMV6
Scaffold attachment factor B, isoform B

1

3

Small-scale

0.445

High

1343225

ATX2
Ataxin-2 homolog

1

3

Small-scale

0.445

High

1464082

Q9V3P3
LD45860p

1

1

Small-scale

0.445

High

1466135

PSA3
Proteasome subunit alpha type-3

1

2

Small-scale

0.445

High

1480135

UFD4
E3 ubiquitin-protein ligase Ufd4

1

7

High-throughput

0.445

High

1486410

SMD1
Probable small nuclear ribonucleoprotein Sm D1

1

1

High-throughput

0.445

High

1488564

Q9VY44
mRNA-capping enzyme [Includes: mRNA 5'-triphosphate monophosphatase

1

4

High-throughput

0.445

High

1489993

Q9W414
Regulatory particle triple-A ATPase 4

1

2

Small-scale

0.445

High

1486429

Q9VU12
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

1490364

CRK
Adapter molecule Crk

1

18

High-throughput

0.439

High

683576

YEMA
yemanuclein

1

0

High-throughput

0.426

High

831939

PEP
Zinc finger protein on ecdysone puffs

1

0

Small-scale

0.426

High

1265222

ADRM1
Proteasomal ubiquitin receptor ADRM1 homolog

1

0

Small-scale

0.426

High

1266415

Q7K4C7
choline-phosphate cytidylyltransferase

1

0

High-throughput

0.426

High

1474488

Q9VG84
DNA ligase

1

0

High-throughput

0.426

High

1482568

Q9VNC1
Large ribosomal subunit protein mL44

1

0

High-throughput

0.426

High

1489859

INT4
Integrator complex subunit 4

1

0

High-throughput

0.426

High

1305516

Q8IQI1
Uncharacterized protein, isoform A

1

1

High-throughput

0.417

High

234660

VINC
Vinculin

1

6

High-throughput

0.407

High

578198

ENO
Enolase

1

4

Small-scale

0.407

High

612427

ACTN
Alpha-actinin, sarcomeric

1

5

High-throughput

0.407

High

875331

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.407

High

1171557

MY31D
Unconventional myosin ID

1

16

High-throughput

0.407

High

1262252

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

2

Small-scale

0.407

High

1267355

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

1

Small-scale

0.407

High

1344042

CAPON
Capon-like protein

1

12

High-throughput

0.407

High

1374829

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

Small-scale

0.407

High

1464502

Q9V3V6
26S proteasome regulatory complex subunit p50

1

6

Small-scale

0.407

High

1464825

Q9V3Z4
GH11341p

1

2

Small-scale

0.407

High

1466920

HEMH
Ferrochelatase, mitochondrial

1

3

Small-scale

0.407

High

1479248

Q9VK60
GH25425p

1

1

Small-scale

0.407

High

1483872

AIFM1
Putative apoptosis-inducing factor 1, mitochondrial

1

1

Small-scale

0.407

High

1487222

Q9VVA7
Tumor suppressor protein 101

1

2

Small-scale

0.407

High

1488413

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

5

Small-scale

0.407

High

1490074

Q9W4M4
Uncharacterized protein

1

3

High-throughput

0.407

High

1343959

Q8SXQ5
Glutaredoxin-related protein 5, mitochondrial

2

0

High-throughput

0.310

High

1486705

Q9VUG4
GEO12017p1

2

0

High-throughput

0.310

High

1489267

Q9W0A2
MIP23106p

2

0

High-throughput

0.310

High

874953

IF4E
Eukaryotic translation initiation factor 4E1

2

0

Small-scale

0.298

High

723857

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.265

Low

1266951

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

1428041

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.265

Low

1479468

DGT2
Augmin complex subunit dgt2

1

0

High-throughput

0.265

Low

1484582

Q9VR24
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1489831

Q9W335
Translocon-associated protein subunit alpha

1

0

High-throughput

0.253

Low

118481

M9NEA1
Stathmin, isoform D

1

0

Small-scale

0.232

Low

874412

RS25
Small ribosomal subunit protein eS25

1

0

Small-scale

0.232

Low

1172915

RS5A
Small ribosomal subunit protein uS7A

1

0

Small-scale

0.232

Low

1262504

Q7JWE2
GH09427p

1

0

High-throughput

0.232

Low

1264865

Q7K1H9
GH07575p

1

0

High-throughput

0.232

Low

1302832

NOL6
Nucleolar protein 6

1

0

High-throughput

0.232

Low

1466046

RL31
Large ribosomal subunit protein eL31

1

0

Small-scale

0.232

Low

1466677

SRRT
Serrate RNA effector molecule homolog

1

0

Small-scale

0.232

Low

1472348

Q9VE78
Corona

1

0

High-throughput

0.232

Low

1475340

Q9VGW9
Large ribosomal subunit protein mL37

1

0

High-throughput

0.232

Low

1477294

Q9VIB5
Carboxylic ester hydrolase

1

0

Small-scale

0.232

Low

1477333

Q9VID7
Lethal

1

0

Small-scale

0.232

Low

1484121

Q9VQE8
TBP-related factor 5

1

0

High-throughput

0.232

Low

1487232

CCD22
Coiled-coil domain-containing protein 22 homolog

1

0

High-throughput

0.232

Low

1489812

Q9W2V9
LD40707p

1

0

Small-scale

0.232

Low

1490048

Q9W4C1
IP13321p

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025