Protein: UBP19
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)

Gene: UBP19, USP19
Organism: Homo sapiens
Interactions: 136
UniProt ID: O94966

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0016579 - protein deubiquitination
GO:0031647 - regulation of protein stability

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

301354

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

6

20

Small-scale

0.939

High

301351

HS90A
Heat shock protein HSP 90-alpha

5

11

Small-scale

0.727

High

301416

SIAH1
E3 ubiquitin-protein ligase SIAH1

4

13

Small-scale

0.705

High

259907

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

4

6

High-throughput

0.699

High

301428

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

19

High-throughput

0.665

High

199076

SIAH2
E3 ubiquitin-protein ligase SIAH2

2

20

Small-scale

0.640

High

301397

IRF3
Interferon regulatory factor 3

2

2

High-throughput

0.628

High

301447

DOCK5
Dedicator of cytokinesis protein 5

2

3

High-throughput

0.628

High

301459

CRYL1
Lambda-crystallin homolog

2

1

High-throughput

0.628

High

301385

BIRC3
Baculoviral IAP repeat-containing protein 3

2

18

Small-scale

0.624

High

301380

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

16

Small-scale

0.618

High

301458

AURKC
Aurora kinase C

3

17

High-throughput

0.609

High

301394

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

2

7

High-throughput

0.601

High

301377

DMWD
Dystrophia myotonica WD repeat-containing protein

1

12

High-throughput

0.595

High

301414

SYVN1
E3 ubiquitin-protein ligase synoviolin

2

12

Small-scale

0.584

High

301434

FER3L
Fer3-like protein

2

6

High-throughput

0.574

High

301347

PH4H
Phenylalanine-4-hydroxylase

2

0

Small-scale

0.559

High

301411

CD37L
Hsp90 co-chaperone Cdc37-like 1

1

2

High-throughput

0.554

High

301417

NUDC3
NudC domain-containing protein 3

1

1

High-throughput

0.553

High

301402

HIF1A
Hypoxia-inducible factor 1-alpha

1

11

Small-scale

0.552

High

301432

NEUL4
Neuralized-like protein 4

2

2

High-throughput

0.537

High

118659

AIP
AH receptor-interacting protein

1

8

High-throughput

0.536

High

149811

RFXK
DNA-binding protein RFXANK

1

6

High-throughput

0.536

High

301343

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

High-throughput

0.536

High

301352

HS90B
Heat shock protein HSP 90-beta

1

12

High-throughput

0.536

High

301376

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

7

High-throughput

0.536

High

301382

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.536

High

301383

SKP2
S-phase kinase-associated protein 2

1

3

High-throughput

0.536

High

301398

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

2

High-throughput

0.536

High

301401

CDC37
Hsp90 co-chaperone Cdc37

1

2

High-throughput

0.536

High

301420

DDX60
Probable ATP-dependent RNA helicase DDX60

1

17

High-throughput

0.536

High

301437

DNJC7
DnaJ homolog subfamily C member 7

1

8

High-throughput

0.536

High

301446

RPAP3
RNA polymerase II-associated protein 3

1

9

High-throughput

0.536

High

301455

FKBPL
FK506-binding protein-like

1

11

High-throughput

0.536

High

301456

G3BP2
Ras GTPase-activating protein-binding protein 2

1

3

High-throughput

0.536

High

301346

HERC2
E3 ubiquitin-protein ligase HERC2

1

18

High-throughput

0.515

High

301349

CDK1
Cyclin-dependent kinase 1

1

9

High-throughput

0.515

High

301359

RO52
E3 ubiquitin-protein ligase TRIM21

1

20

High-throughput

0.515

High

301361

HMOX2
Heme oxygenase 2

1

1

High-throughput

0.515

High

301371

XPO2
Exportin-2

1

3

High-throughput

0.515

High

301373

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

2

High-throughput

0.515

High

301389

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

2

High-throughput

0.515

High

301400

AAAT
Neutral amino acid transporter B(0)

1

1

High-throughput

0.515

High

301422

ATAD1
Outer mitochondrial transmembrane helix translocase

1

13

High-throughput

0.515

High

301426

GCN1
Stalled ribosome sensor GCN1

1

16

High-throughput

0.515

High

301436

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.515

High

301444

UN45A
Protein unc-45 homolog A

1

11

High-throughput

0.515

High

301462

SRPRB
Signal recognition particle receptor subunit beta

1

4

High-throughput

0.515

High

245658

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

278578

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

301357

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

Small-scale

0.513

High

301424

FA83F
Protein FAM83F

1

0

High-throughput

0.513

High

301425

CP2W1
Cytochrome P450 2W1

1

0

High-throughput

0.513

High

301441

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

0

High-throughput

0.513

High

301350

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.493

High

301372

TMM33
Transmembrane protein 33

1

0

High-throughput

0.493

High

301379

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.493

High

301399

SF3B3
Splicing factor 3B subunit 3

1

4

High-throughput

0.489

High

301406

NXNL2
Nucleoredoxin-like protein 2

1

1

High-throughput

0.489

High

301421

TTC9C
Tetratricopeptide repeat protein 9C

1

8

High-throughput

0.489

High

301360

FLNA
Filamin-A

1

7

Small-scale

0.481

High

301393

CKAP5
Cytoskeleton-associated protein 5

1

8

Small-scale

0.481

High

128380

DNM1L
Dynamin-1-like protein

1

2

Small-scale

0.479

High

177638

BIRC5
Baculoviral IAP repeat-containing protein 5

1

15

Small-scale

0.479

High

201151

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

6

Small-scale

0.479

High

213425

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

12

High-throughput

0.479

High

262208

ULK1
Serine/threonine-protein kinase ULK1

1

12

Small-scale

0.479

High

301355

HSP7C
Heat shock cognate 71 kDa protein

1

6

Small-scale

0.479

High

301356

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

Small-scale

0.479

High

301362

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.479

High

301363

HSP74
Heat shock 70 kDa protein 4

1

11

Small-scale

0.479

High

301364

TGFR1
TGF-beta receptor type-1

1

11

Small-scale

0.479

High

301365

CCNF
Cyclin-F

1

10

High-throughput

0.479

High

301366

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

301369

MAOX
NADP-dependent malic enzyme

1

3

Small-scale

0.479

High

301374

XIAP
E3 ubiquitin-protein ligase XIAP

1

20

Small-scale

0.479

High

301375

EWS
RNA-binding protein EWS

1

4

Small-scale

0.479

High

301381

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

6

High-throughput

0.479

High

301384

SMAD4
Mothers against decapentaplegic homolog 4

1

15

High-throughput

0.479

High

301386

BIRC2
Baculoviral IAP repeat-containing protein 2

1

20

Small-scale

0.479

High

301387

SQSTM
Sequestosome-1

1

6

Small-scale

0.479

High

301388

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.479

High

301390

CUL3
Cullin-3

1

18

High-throughput

0.479

High

301392

CUL4B
Cullin-4B

1

18

High-throughput

0.479

High

301395

BECN1
Beclin-1

1

3

Small-scale

0.479

High

301396

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

13

Small-scale

0.479

High

301408

Q6PK50
Heat shock protein HSP 90-beta

1

12

High-throughput

0.479

High

301423

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

2

Small-scale

0.479

High

301429

FAF2
FAS-associated factor 2

1

5

Small-scale

0.479

High

301440

DERL1
Derlin-1

1

1

Small-scale

0.479

High

301442

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

1

Small-scale

0.479

High

301450

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.479

High

301451

SE1L1
Protein sel-1 homolog 1

1

4

Small-scale

0.479

High

301452

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

301453

TBK1
Serine/threonine-protein kinase TBK1

1

15

Small-scale

0.479

High

301454

HERC5
E3 ISG15--protein ligase HERC5

1

10

Small-scale

0.479

High

301457

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

Small-scale

0.479

High

301460

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

301353

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.470

High

301367

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.470

High

301368

ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

2

High-throughput

0.470

High

301403

H31T
Histone H3.1t

1

3

High-throughput

0.470

High

301431

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.470

High

301433

DOCK7
Dedicator of cytokinesis protein 7

1

3

High-throughput

0.470

High

301448

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

2

High-throughput

0.470

High

301461

TNPO3
Transportin-3

1

4

High-throughput

0.470

High

301345

ECEL1
Endothelin-converting enzyme-like 1

1

0

Small-scale

0.460

High

301344

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.458

High

301358

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

301409

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

301415

TCAM1
TIR domain-containing adapter molecule 1

1

0

Small-scale

0.458

High

301439

AASD1
Alanyl-tRNA editing protein Aarsd1

1

0

High-throughput

0.458

High

271992

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

14

Small-scale

0.439

High

301435

RING2
E3 ubiquitin-protein ligase RING2

1

20

Small-scale

0.439

High

301438

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

7

Small-scale

0.439

High

204858

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.437

High

301348

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

301370

RORG
Nuclear receptor ROR-gamma

1

8

Small-scale

0.437

High

301391

CUL4A
Cullin-4A

1

18

High-throughput

0.437

High

301410

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

301413

MAVS
Mitochondrial antiviral-signaling protein

1

14

Small-scale

0.437

High

301427

HDAC2
Histone deacetylase 2

1

14

Small-scale

0.437

High

301445

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.437

High

301449

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

301404

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

2

High-throughput

0.407

High

301418

FUND1
FUN14 domain-containing protein 1

1

0

Small-scale

0.301

High

301405

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.279

Low

301419

CC117
Coiled-coil domain-containing protein 117

1

0

High-throughput

0.279

Low

301464

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

301430

SAAL1
Protein SAAL1

1

0

High-throughput

0.269

Low

301378

LTOR4
Ragulator complex protein LAMTOR4

1

0

Small-scale

0.251

Low

207403

LAT
Linker for activation of T-cells family member 1

1

0

High-throughput

0.249

Low

301412

DET1
DET1 homolog

1

0

High-throughput

0.249

Low

301443

SPNS1
Protein spinster homolog 1

1

0

High-throughput

0.249

Low

301463

KPTN
KICSTOR complex protein kaptin

1

0

High-throughput

0.249

Low

301407

PTCRA
Pre T-cell antigen receptor alpha

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024