Protein: MED10
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (dMED10) (dTRAP15)

Gene: MED10
Organism: Drosophila melanogaster
Interactions: 73
UniProt ID: Q9GYU7

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1321550

MED6
Mediator of RNA polymerase II transcription subunit 6

2

4

High-throughput

0.737

High

1427976

MED7
Mediator of RNA polymerase II transcription subunit 7

2

6

High-throughput

0.737

High

1428009

MED14
Mediator of RNA polymerase II transcription subunit 14

2

3

High-throughput

0.737

High

1267053

MED29
Mediator of RNA polymerase II transcription subunit 29

3

1

High-throughput

0.646

High

1427996

MED4
Mediator of RNA polymerase II transcription subunit 4

3

1

Small-scale

0.629

High

1428014

MED21
Mediator of RNA polymerase II transcription subunit 21

1

1

Small-scale

0.590

High

1428001

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.575

High

1428003

MED12
Mediator of RNA polymerase II transcription subunit 12

1

2

High-throughput

0.575

High

58485

MED8
Mediator of RNA polymerase II transcription subunit 8

2

1

High-throughput

0.571

High

1019284

MED20
Mediator of RNA polymerase II transcription subunit 20

2

1

High-throughput

0.571

High

1377771

EBI
F-box-like/WD repeat-containing protein ebi

2

1

High-throughput

0.571

High

1427982

MED17
Mediator of RNA polymerase II transcription subunit 17

2

1

High-throughput

0.571

High

1427991

MED27
Mediator of RNA polymerase II transcription subunit 27

2

1

High-throughput

0.571

High

1428002

MED11
Mediator of RNA polymerase II transcription subunit 11

2

1

High-throughput

0.571

High

1428005

BAP60
Brahma-associated protein of 60 kDa

2

1

High-throughput

0.571

High

1428008

MED30
Mediator of RNA polymerase II transcription subunit 30

2

1

High-throughput

0.571

High

1428010

MED23
Mediator of RNA polymerase II transcription subunit 23

2

1

High-throughput

0.571

High

1428011

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

High-throughput

0.571

High

1428015

MED18
Mediator of RNA polymerase II transcription subunit 18

2

1

High-throughput

0.571

High

1261402

Q7JQT8
LD41464p

2

0

High-throughput

0.547

High

1427983

Q9VF03
Brahma associated protein 155 kDa

2

0

High-throughput

0.547

High

1378903

Q960F7
SD03629p

2

1

High-throughput

0.521

High

1427998

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

1

High-throughput

0.521

High

1428013

Q9W4I4
Helix loop helix protein 4C, isoform A

1

0

High-throughput

0.486

High

1428016

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.479

High

1427987

Q9VKS9
GH10507p

1

1

High-throughput

0.464

High

1269607

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.445

High

1302883

MED31
Mediator of RNA polymerase II transcription subunit 31

1

2

High-throughput

0.445

High

1427980

MED25
Mediator of RNA polymerase II transcription subunit 25

1

2

High-throughput

0.445

High

1427992

MED1
Mediator of RNA polymerase II transcription subunit 1

1

1

High-throughput

0.445

High

1427997

MED24
Mediator of RNA polymerase II transcription subunit 24

1

1

High-throughput

0.445

High

1427999

CDK8
Cyclin-dependent kinase 8

1

4

High-throughput

0.445

High

1268999

Q7KSA4
Uncharacterized protein, isoform C

1

1

High-throughput

0.439

High

1427988

Q9VKT1
GH11711p

1

1

High-throughput

0.439

High

56988

A1ZAK9
P-element somatic inhibitor, isoform A

1

1

High-throughput

0.437

High

1427994

Q9VR42
Serine/threonine-protein kinase RIO3

1

1

High-throughput

0.437

High

197466

O18353
CHIP

1

0

High-throughput

0.426

High

674037

BRM
ATP-dependent helicase brm

1

0

High-throughput

0.426

High

1171882

Q24090
GH08712p

1

0

High-throughput

0.426

High

1263889

Q7K012
Brahma associated protein 55kD

1

0

High-throughput

0.426

High

1303609

OSA
Trithorax group protein osa

1

0

High-throughput

0.426

High

1306400

INDRA
Zinc finger protein indra

1

0

High-throughput

0.426

High

1428006

Q9VYK0
Smrter, isoform D

1

0

High-throughput

0.426

High

1427977

Q9I7I6
IP13792p

1

1

High-throughput

0.417

High

53579

A1Z813
Secretory 24AB, isoform A

1

1

High-throughput

0.407

High

56944

A1ZAK7
LD35640p

1

1

High-throughput

0.407

High

1343886

Q8SXP8
TAR DNA-binding protein 43

1

1

High-throughput

0.407

High

1409384

Q9BIW6
Brahma-associated protein 111kD

1

1

High-throughput

0.407

High

1427990

Q9VNF8
Protein transport protein SEC23

1

1

High-throughput

0.407

High

1344554

Q8SYK4
RE55691p

2

0

High-throughput

0.310

High

1428004

Q9VXX0
GH05991p

2

0

High-throughput

0.310

High

900651

DSH
Segment polarity protein dishevelled

2

0

High-throughput

0.298

High

1321503

ENC
Protein encore

2

0

High-throughput

0.298

High

1346407

MESD
LDLR chaperone boca

2

0

High-throughput

0.298

High

1427978

LAR4
La-related protein Larp4B

2

0

High-throughput

0.298

High

1427981

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

2

0

High-throughput

0.298

High

1427989

Q9VL29
GEO11246p1

2

0

High-throughput

0.298

High

1428000

Q9VUB7
PAX-interacting protein 1

2

0

High-throughput

0.298

High

968547

CALM
Calmodulin

1

0

High-throughput

0.265

Low

1172240

DNAJ1
DnaJ protein homolog 1

1

0

High-throughput

0.265

Low

1427979

Q9VCS1
IP04268p

1

0

High-throughput

0.265

Low

1427984

Q9VG44
RE14195p

1

0

High-throughput

0.265

Low

1427985

Q9VHT8
RE26525p

1

0

High-throughput

0.265

Low

1427993

Q9VQV7
Centrosomal protein of 97 kDa

1

0

High-throughput

0.251

Low

1377319

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low

1427986

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

84976

B7Z126
non-specific serine/threonine protein kinase

1

0

High-throughput

0.232

Low

1069266

Q0E8G6
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.232

Low

1069926

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.232

Low

1346010

ENA
Protein enabled

1

0

High-throughput

0.232

Low

1427995

Q9VR43
AT09986p

1

0

High-throughput

0.232

Low

1428007

Q9W0L7
ubiquitinyl hydrolase 1

1

0

High-throughput

0.232

Low

1428012

Q9W3G1
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025