Protein: SH2B2
SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS)

Gene: SH2B2
Organism: Mus musculus
Interactions: 10
UniProt ID: Q9JID9

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0001726 - ruffle
GO:0001922 - B-1 B cell homeostasis
GO:0005068 - transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

581968

INSR
Insulin receptor

2

20

Small-scale

0.754

High

1362463

ASB6
Ankyrin repeat and SOCS box protein 6

1

6

Small-scale

0.713

High

1223372

FGFR3
Fibroblast growth factor receptor 3

1

20

Small-scale

0.700

High

651580

CBL
E3 ubiquitin-protein ligase CBL

4

20

Small-scale

0.671

High

1221258

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

1224148

SRBS1
Sorbin and SH3 domain-containing protein 1

1

20

Small-scale

0.618

High

1242565

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

20

Small-scale

0.618

High

1189170

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

1189412

PDLI7
PDZ and LIM domain protein 7

1

20

Small-scale

0.479

High

1282956

CBLC
E3 ubiquitin-protein ligase CBL-C

1

20

Small-scale

0.437

High


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Last updated: 11Aug2025