Interactor 1: PARP9 (Q8IXQ6)
Protein mono-ADP-ribosyltransferase PARP9 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein) (Poly [ADP-ribose] polymerase 9) (PARP-9)
Gene: PARP9

Interactor 2: DTX3L (Q8TDB6)
E3 ubiquitin-protein ligase DTX3L (EC 2.3.2.27) (B-lymphoma- and BAL-associated protein) (Protein deltex-3-like) (RING-type E3 ubiquitin transferase DTX3L) (Rhysin-2) (Rhysin2)
Gene: DTX3L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 26479788, 28514442, 32937373, 32948590, 33961781, 35037691, 24886089, 28525742, 12670957, 37071682
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0002230 - positive regulation of defense response to virus by host
GO:0004857 - enzyme inhibitor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 13 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 854
Hs

1 740
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024