HitPredict

Interactor 1: PHC1 (P78364)
Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)
Gene: PHC1

Interactor 2: RYBP (Q8N488)
RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)
Gene: RYBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0008270 - zinc ion binding and 1 others more... GO:0031519 - PcG protein complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1004 Hs			1 228
+	Hs
		1006858 PHC1_HUMAN (1-1004): 1.15e-86: 302: 100.00		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89
+	Hs
		1314037 SCMH1_HUMAN (577-1003): 6.59e-38: 153: 16.23		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89
+	Hs
		64828 F186A_HUMAN (20-817): 9.13e-22: 104: 12.25		RYBP_HUMAN (1-228): 2.8e-61: 193: 100.00
+	Dm
		814673 PHP_DROME (30-1003): 3.79e-29: 128: 14.24		Q9W215_DROME (3-197): 3.07e-42: 142: 37.95
+	Hs
		1312458 PHC2_HUMAN (45-677): 1.37e-10: 67.7: 10.11		RYBP_HUMAN (1-228): 2.8e-61: 193: 100.00
+	Hs
		1325991 PHC3_HUMAN (22-667): 2.86e-10: 66.5: 10.25		RYBP_HUMAN (1-228): 2.8e-61: 193: 100.00
+	Hs
		1312456 PHC2_HUMAN (45-677): 1.37e-10: 67.7: 10.11		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89
+	Hs
		1314020 PHC3_HUMAN (22-667): 2.86e-10: 66.5: 10.25		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89
+	Dm
		1479066 SMBT_DROME (921-1002): 9.61e-13: 74.7: 31.71		Q9W215_DROME (3-197): 3.07e-42: 142: 37.95