Protein: SCMH1
Polycomb protein SCMH1 (Sex comb on midleg homolog 1)

Gene: SCMH1
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q96GD3

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0031507 - heterochromatin formation
GO:0042393 - histone binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1006867

PHC1
Polyhomeotic-like protein 1

4

19

High-throughput

0.903

High

1312481

PHC2
Polyhomeotic-like protein 2

3

19

High-throughput

0.864

High

1336925

PHC3
Polyhomeotic-like protein 3

2

18

High-throughput

0.789

High

1218281

SMBT2
Scm-like with four MBT domains protein 2

2

18

High-throughput

0.783

High

1391694

SMBT1
Scm-like with four MBT domains protein 1

2

19

High-throughput

0.783

High

766111

PCGF2
Polycomb group RING finger protein 2

4

20

High-throughput

0.699

High

1391687

SCMH1
Polycomb protein SCMH1

1

19

High-throughput

0.698

High

765790

BMI1
Polycomb complex protein BMI-1

4

20

High-throughput

0.694

High

1247617

SAMD1
Sterile alpha motif domain-containing protein 1

1

8

High-throughput

0.691

High

1391697

SCML2
Sex comb on midleg-like protein 2

1

19

High-throughput

0.691

High

1391689

RING2
E3 ubiquitin-protein ligase RING2

4

20

Small-scale

0.689

High

338930

CBX6
Chromobox protein homolog 6

2

20

High-throughput

0.628

High

129787

CBX4
E3 SUMO-protein ligase CBX4

2

20

High-throughput

0.611

High

451700

PGK2
Phosphoglycerate kinase 2

2

0

High-throughput

0.602

High

977794

ACTA
Actin, aortic smooth muscle

2

2

High-throughput

0.574

High

1201028

ACTBL
Beta-actin-like protein 2

2

2

High-throughput

0.574

High

848972

MAGAC
Melanoma-associated antigen 12

1

2

High-throughput

0.573

High

1391696

UBQL1
Ubiquilin-1

1

3

High-throughput

0.573

High

334632

LYPA2
Acyl-protein thioesterase 2

1

1

High-throughput

0.541

High

900090

FXR1
RNA-binding protein FXR1

1

7

High-throughput

0.541

High

900457

FXR2
RNA-binding protein FXR2

1

7

High-throughput

0.541

High

1364963

TSC1
Hamartin

1

6

High-throughput

0.541

High

1391688

MAML3
Mastermind-like protein 3

1

2

High-throughput

0.541

High

1391693

UBQL4
Ubiquilin-4

1

2

High-throughput

0.541

High

591785

H2AX
Histone H2AX

1

5

High-throughput

0.536

High

1055841

RING1
E3 ubiquitin-protein ligase RING1

1

20

High-throughput

0.536

High

1132224

CBX2
Chromobox protein homolog 2

1

20

High-throughput

0.536

High

1391692

CBX8
Chromobox protein homolog 8

1

20

High-throughput

0.536

High

897468

TOB1
Protein Tob1

1

0

High-throughput

0.518

High

961624

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

1033145

EWS
RNA-binding protein EWS

1

0

High-throughput

0.518

High

329958

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

0

High-throughput

0.513

High

1328751

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

1

High-throughput

0.494

High

955469

CDC42
Cell division control protein 42 homolog

1

1

High-throughput

0.489

High

984239

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

4

High-throughput

0.489

High

260296

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.479

High

998673

H31
Histone H3.1

1

20

High-throughput

0.479

High

1017110

H33
Histone H3.3

1

20

High-throughput

0.479

High

1185936

PCGF3
Polycomb group RING finger protein 3

1

20

High-throughput

0.479

High

1204629

BCORL
BCL-6 corepressor-like protein 1

1

11

High-throughput

0.479

High

1250637

BCOR
BCL-6 corepressor

1

16

High-throughput

0.479

High

1286253

PCGF5
Polycomb group RING finger protein 5

1

20

High-throughput

0.479

High

1314037

YAF2
YY1-associated factor 2

1

11

High-throughput

0.479

High

1391690

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

1391699

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

1391691

FBRS
Probable fibrosin-1

1

4

High-throughput

0.437

High

505968

MYZAP
Myocardial zonula adherens protein

1

1

High-throughput

0.417

High

1391695

HPCL4
Hippocalcin-like protein 4

2

0

High-throughput

0.316

High

1391698

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.282

High

1232003

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.251

Low

602257

TMM11
Transmembrane protein 11, mitochondrial

1

0

High-throughput

0.238

Low

621506

HXK1
Hexokinase-1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025