HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: THOC3 (Q96J01)
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)
Gene: THOC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 33961781, 37500615
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 351
+	Hs
		1394575 TCPH_HUMAN (4-532): 0: 591: 34.08		THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00
+	Hs
		1007162 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45
+	Hs
		1291941 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52
+	Hs
		1007118 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52
+	Hs
		965190 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75
+	Hs
		882014 TCPG_HUMAN (3-532): 0: 561: 28.33		WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52
+	Hs
		964840 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75
+	Hs
		881861 TCPG_HUMAN (3-532): 0: 561: 28.33		WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75
+	Hs
		1407594 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (215-351): 1.09e-40: 150: 22.22
+	Hs
		1334162 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (4-168): 2.05e-40: 148: 19.28
+	Hs
		1007305 TCPB_HUMAN (1-535): 0: 586: 100.00		NLE1_HUMAN (215-351): 1.09e-40: 150: 22.22
+	Hs
		1007146 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (4-168): 2.05e-40: 148: 19.28
+	Hs
		882038 TCPG_HUMAN (3-532): 0: 561: 28.33		POC1A_HUMAN (4-168): 2.05e-40: 148: 19.28
+	Hs
		1007196 TCPB_HUMAN (1-535): 0: 586: 100.00		SNR40_HUMAN (1-122): 1.69e-19: 90.1: 19.85
+	Hs
		1007186 TCPB_HUMAN (1-535): 0: 586: 100.00		FBXW7_HUMAN (251-351): 1.11e-17: 86.2: 15.53
+	Hs
		1407542 TCPH_HUMAN (4-532): 0: 591: 34.08		KTNB1_HUMAN (47-287): 1.48e-12: 70.5: 24.50
+	Hs
		1007244 TCPB_HUMAN (1-535): 0: 586: 100.00		KTNB1_HUMAN (47-287): 1.48e-12: 70.5: 24.50
+	Hs
		845257 TCPG_HUMAN (3-532): 0: 561: 28.33		LIS1_HUMAN (262-351): 1.75e-20: 93.5: 20.88
+	Hs
		1407533 TCPH_HUMAN (4-532): 0: 591: 34.08		TBL1Y_HUMAN (2-84): 1.2e-09: 61.6: 13.25
+	Hs
		1007231 TCPB_HUMAN (1-535): 0: 586: 100.00		TBL1Y_HUMAN (2-84): 1.2e-09: 61.6: 13.25