HitPredict

Interactor 1: THOC3 (Q96J01)
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)
Gene: THOC3

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 37500615
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 351 Hs			1 543
+	Hs
		1291941 WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		965190 WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		882090 THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		882051 POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		882014 WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		876117 THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		876081 POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610828 THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610789 POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		881861 WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		1407594 NLE1_HUMAN (215-351): 1.09e-40: 150: 22.22		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		610750 WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		875898 WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610601 WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		876199 NLE1_HUMAN (215-351): 1.09e-40: 150: 22.22		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		899527 THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899492 POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899463 WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899326 WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899608 NLE1_HUMAN (215-351): 1.09e-40: 150: 22.22		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79