Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (Ser-473 kinase) (S473K) (p460)
Gene: PRKDC
Interactor 2: DCR1C (Q96SD1)
Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein)
Gene: DCLRE1C
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.969 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11955432, 15456891, 16857680, 31900314, 33961781, 15936993, 22529269 |
| Identification Methods | pull down, enzymatic study, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA-PKcs_N~DRMBL, DNAPKcs_CC3~DRMBL |
| Common GO terms | GO:0000723 - telomere maintenance GO:0005654 - nucleoplasm GO:0006303 - double-strand break repair via nonhomologous end joining GO:0070419 - nonhomologous end joining complex |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
