Protein: DCR1B
5' exonuclease Apollo (EC 3.1.-.-) (Beta-lactamase DCLRE1B) (EC 3.5.2.6) (DNA cross-link repair 1B protein) (SNM1 homolog B) (SNMIB) (hSNM1B)

Gene: DCR1B, DCLRE1B
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9H816

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0003684 - damaged DNA binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149991

TERF2
Telomeric repeat-binding factor 2

10

1

Small-scale

0.756

High

1436047

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

6

0

Small-scale

0.701

High

1008354

PRKDC
DNA-dependent protein kinase catalytic subunit

1

4

High-throughput

0.691

High

1436042

DCR1B
5' exonuclease Apollo

1

16

Small-scale

0.618

High

1388736

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

2

High-throughput

0.601

High

532972

CH60
60 kDa heat shock protein, mitochondrial

2

0

Small-scale

0.585

High

407714

S100B
Protein S100-B

2

0

High-throughput

0.576

High

928552

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.536

High

1211653

FBP1L
Formin-binding protein 1-like

1

1

High-throughput

0.536

High

1436050

PSF2
DNA replication complex GINS protein PSF2

1

0

Small-scale

0.529

High

686651

ELAV4
ELAV-like protein 4

1

3

High-throughput

0.515

High

843990

HD
Huntingtin

1

1

High-throughput

0.515

High

326191

FSBP
Fibrinogen silencer-binding protein

1

0

High-throughput

0.513

High

1327462

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.513

High

1412510

TINF2
TERF1-interacting nuclear factor 2

1

0

High-throughput

0.513

High

1436043

KANL2
KAT8 regulatory NSL complex subunit 2

1

0

High-throughput

0.513

High

1436045

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.513

High

1401167

SPAG5
Sperm-associated antigen 5

1

1

Small-scale

0.501

High

387463

APOE
Apolipoprotein E

1

0

High-throughput

0.493

High

890055

PSN1
Presenilin-1

1

0

High-throughput

0.493

High

896888

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

927137

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

1279751

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1365183

NDRG1
Protein NDRG1

1

0

High-throughput

0.493

High

1436044

TYDP1
Tyrosyl-DNA phosphodiesterase 1

1

0

High-throughput

0.493

High

1419227

TRI54
Tripartite motif-containing protein 54

1

3

High-throughput

0.481

High

537922

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.479

High

799477

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

892946

MRE11
Double-strand break repair protein MRE11

1

1

Small-scale

0.479

High

980334

H4
Histone H4

1

4

High-throughput

0.479

High

1118598

TBB2A
Tubulin beta-2A chain

1

1

Small-scale

0.479

High

1314423

SLX4
Structure-specific endonuclease subunit SLX4

1

3

Small-scale

0.479

High

1369774

RAD50
DNA repair protein RAD50

1

2

Small-scale

0.479

High

1417476

FACD2
Fanconi anemia group D2 protein

1

3

Small-scale

0.479

High

933733

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.458

High

1005103

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1399307

MUS81
Structure-specific endonuclease subunit MUS81

1

0

Small-scale

0.458

High

761885

HSP74
Heat shock 70 kDa protein 4

1

5

Small-scale

0.437

High

61640

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.426

High

786262

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.426

High

1436046

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.426

High

1288885

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

1436049

TFR2
Transferrin receptor protein 2

1

0

Small-scale

0.297

High

1244012

F199X
Protein FAM199X

1

0

High-throughput

0.279

Low

1259684

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.279

Low

1436048

S39AA
Zinc transporter ZIP10

1

0

High-throughput

0.279

Low

301705

WFS1
Wolframin

1

0

High-throughput

0.268

Low

642294

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025